{"title":"在一个不断发展的领域中，预防性颅内照射对广泛期小细胞肺癌癌症的作用是什么？","authors":"A. Bang, R. MacRae","doi":"10.21037/TRO.2019.03.01","DOIUrl":null,"url":null,"abstract":"The role of prophylactic cranial irradiation (PCI) for extensive-stage small-cell lung cancer (ES-SCLC) has evolved since the publication of two phase III randomized control trials in the past decade. Despite significant evidence demonstrating improvements in survival and rates of developing brain metastasis in the limited-stage setting, there was no clear evidence supporting its use for ES-SCLC until 2007, with the publication of the European Organization for Research and Treatment of Cancer (EORTC) study.","PeriodicalId":93236,"journal":{"name":"Therapeutic radiology and oncology","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-03-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.21037/TRO.2019.03.01","citationCount":"0","resultStr":"{\"title\":\"What is the role of prophylactic cranial irradiation for extensive-stage small-cell lung cancer in an evolving field?\",\"authors\":\"A. Bang, R. MacRae\",\"doi\":\"10.21037/TRO.2019.03.01\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"The role of prophylactic cranial irradiation (PCI) for extensive-stage small-cell lung cancer (ES-SCLC) has evolved since the publication of two phase III randomized control trials in the past decade. Despite significant evidence demonstrating improvements in survival and rates of developing brain metastasis in the limited-stage setting, there was no clear evidence supporting its use for ES-SCLC until 2007, with the publication of the European Organization for Research and Treatment of Cancer (EORTC) study.\",\"PeriodicalId\":93236,\"journal\":{\"name\":\"Therapeutic radiology and oncology\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-03-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.21037/TRO.2019.03.01\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Therapeutic radiology and oncology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.21037/TRO.2019.03.01\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Therapeutic radiology and oncology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.21037/TRO.2019.03.01","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
What is the role of prophylactic cranial irradiation for extensive-stage small-cell lung cancer in an evolving field?
The role of prophylactic cranial irradiation (PCI) for extensive-stage small-cell lung cancer (ES-SCLC) has evolved since the publication of two phase III randomized control trials in the past decade. Despite significant evidence demonstrating improvements in survival and rates of developing brain metastasis in the limited-stage setting, there was no clear evidence supporting its use for ES-SCLC until 2007, with the publication of the European Organization for Research and Treatment of Cancer (EORTC) study.
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