老年抑郁症患者代谢综合征的患病率

S. Grover, Rahul Chakravarty, A. Mehra, S. Chakrabarti
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引用次数: 0

摘要

目的:评估代谢综合征(MetS)在老年抑郁症患者中的患病率。方法:采用回顾性研究设计,回顾所有根据《国际疾病分类》第10版诊断为抑郁症的老年患者(年龄≥60岁)的治疗记录,并提取人体测量(身高、体重、腰围和血压[BP])。MetS的诊断符合一致标准。结果:93例患者的数据被纳入研究。研究参与者的平均年龄为65.65岁(标准差[SD]:5.61),平均受教育年限为8.33年(标准差:6.65)。疾病的平均持续时间为70.93(SD:107.39)个月,收集数据时当前发作的平均持续期为5.38(SD:3.54)个月。超过一半(57%)的患者符合MetS的标准。除了超过一半的患者符合MetS标准外,约十分之一(9.7%)符合一项标准,三分之一(32.3%)符合两项标准。MetS最常见的标准包括腰围异常,其次是血压升高、甘油三酯水平异常和高密度脂蛋白异常。空腹血糖水平是最不常见的异常。MetS的存在与较高的教育水平、较高的收入和身体共病的存在有关。结论:考虑到超过一半的老年抑郁症患者也患有代谢综合征,对老年抑郁症患者进行代谢综合征监测以降低未来心血管疾病发病率和死亡率的风险很重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Prevalence of metabolic syndrome in elderly patients with depression
Aim: To assess the prevalence of metabolic syndrome (MetS) in elderly patients with depressive disorder. Methodology: By using retrospective study design, the treatment records of all the elderly patients (aged ≥60 years) diagnosed with depressive disorders diagnosed as per the International Classification of Diseases, 10th Revision, were reviewed and data of patients for fasting blood glucose levels, lipid profile, and anthropometry (height, weight, waist circumference, and blood pressure [BP]) were extracted. The diagnosis of MetS was made as per the consensus criteria. Results: Data of 93 patients were included in the study. The mean age of the study participants was 65.65 (standard deviation [SD]: 5.61) years and the mean number of years of education was 8.33 (SD: 6.65) years. The mean duration of illness was 70.93 (SD: 107.39) months, with the mean duration of the current episode at the time of collection of data as 5.38 (SD: 3.54) months. More than half (57%) of the patients fulfilled the criteria for MetS. Besides more than half of the patients fulfilling the criteria for MetS, about one-tenth (9.7%) fulfilled one criterion, and one-third (32.3%) fulfilled 2 criteria for the MetS. The most common criteria of MetS which was fulfilled included abnormal waist circumference, followed by raised blood pressure, abnormal triglyceride levels, and abnormal high-density lipoprotein. Fasting blood glucose level was the least common abnormality. The presence of MetS was associated with a higher level of education, higher income, and presence of physical comorbidity. Conclusions: Considering that more than half of elderly patients with depressive illness also suffer from MetS, it is important to monitor elderly with depression for MetS, to reduce the risk of future cardiovascular morbidity and mortality.
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