生物机械和生物化学参数与椎体间椎间盘复发疝有关

Q3 Medicine
Евгений Сергеевич Байков, Андрей Александрович Байкалов
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引用次数: 2

摘要

客观的确定退行性脊柱运动节段的自然放射学参数和椎间盘组织的生化变化,这些参数与显微椎间盘切除术后疝复发有显著联系。材料和方法。对L4–L5和L5–S1疝症患者髓核和纤维环组织的MRI、放射学和生化参数进行评估和统计分析。检查了两组患者:第一组(n=50)——有复发性疝,第二组(n=50%)——三年内无复发。后果显微椎间盘切除术后复发性腰椎间盘突出症与以下生物力学参数之间存在显著相关性:椎间盘高度(p=0.001;r=0.69)、节段矢状运动范围(p=001;r=0.62)、腰椎前凸(p=0.001r=0.78)、椎间盘退变分期(p=.001;r=0.46),和疝的类型(p=0.001,r=0.45)。研究组患者髓核和纤维环的蛋白多糖/糖胺聚糖的定量和定性特征存在显著差异,但与复发性疝没有显著相关性(r<0.3)。结论。保留的椎间盘高度、脊柱运动节段的高度灵活性、腰椎前凸的平滑性、中度椎间盘退变和椎间盘突出与显微椎间盘切除术后腰椎间盘突出症的复发有显著联系。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
СВЯЗЬ БИОМЕХАНИЧЕСКИХ И БИОХИМИЧЕСКИХ ПАРАМЕТРОВ ПОЗВОНОЧНО-ДВИГАТЕЛЬНЫХ СЕГМЕНТОВ С РЕЦИДИВОМ ГРЫЖ ПОЯСНИЧНЫХ МЕЖПОЗВОНКОВЫХ ДИСКОВ
Objective. To identify natural radiological parameters of degenerative spinal motion segments and biochemical changes in intervertebral disc tissues, which have a significant connection with the hernia recurrence after microdiscectomy. Material and Methods . The MRI, radiography and biochemical parameters of the nucleus pulpous and annulus fibrosus tissues from patients operated for L4–L5 and L5–S1 herniation were assessed and statistically analyzed. Two groups of patients were examined: Group I (n = 50) – with recurrent hernias, Group II (n = 50) – without recurrence during three years. Results . Significant correlation was observed between recurrent lumbar disc herniation after microdiscectomy and the following biomechanical parameters: height of the intervertebral disc (p = 0.001; r = 0.69), segmental sagittal range of motion (p = 0.001; r = 0.61), lumbar lordosis (p = 0.001, r = 0.78), stage of the intervertebral disc degeneration (p = 0.001; r = 0.46), and type of hernia (p = 0.001, r = 0.45). The quantitative and qualitative characteristics of proteoglycans/glycosaminoglycans of the nucleus pulposus and annulus fibrosus differed significantly in patients of the studied groups, but significant correlation with recurrent hernias was not found (r < 0.3). Conclusion . The preserved intervertebral disc height, hypermobility of the spinal motion segment, the smoothness of the lumbar lordosis, moderate intervertebral disc degeneration, and the disc protrusion have significant connection with the recurrence of lumbar intervertebral disc herniation after microdiscectomy.
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来源期刊
Hirurgia Pozvonochnika
Hirurgia Pozvonochnika Medicine-Anesthesiology and Pain Medicine
CiteScore
0.60
自引率
0.00%
发文量
24
审稿时长
7 weeks
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