Evgenia V. Okladnikova, Vladimir M. Merk, Yuriy А. Krivopalov, Vladimir A. Khorzhevskii, Tatiana Ruksha
{"title":"不确定的树突状细胞肿瘤(IDCT)","authors":"Evgenia V. Okladnikova, Vladimir M. Merk, Yuriy А. Krivopalov, Vladimir A. Khorzhevskii, Tatiana Ruksha","doi":"10.25208/vdv8137","DOIUrl":null,"url":null,"abstract":"Indeterminate dendritic cell tumor (IDCT) is rare histiocytic tumor characterized by the proliferation of indeterminate dendritic cells. It is more often diagnosed in middle-aged people, in approximately equal proportions in men and women. The etiology of IDCT is unknown. Differential diagnosis is carried out with other diseases that mimic IDCT and is important for determining treatment tactics. The present paper presents a clinical case of IDCT in a 48-year-old man. Using only the patient's complaints and examination data was not enough to diagnose the disease. The similarity of skin manifestations in IDCT with other skin pathologies requires an immunohistochemical study of the affected areas for CD1a, CD68, S100, Langerin expression evaluation as well as the presence of Birbeck's granules visulization. Routine histological examination does not sufficient for correct IDCT diagnostics.","PeriodicalId":23618,"journal":{"name":"Vestnik dermatologii i venerologii","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2023-09-06","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Indeterminate dendritic cell tumor (IDCT)\",\"authors\":\"Evgenia V. Okladnikova, Vladimir M. Merk, Yuriy А. Krivopalov, Vladimir A. Khorzhevskii, Tatiana Ruksha\",\"doi\":\"10.25208/vdv8137\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Indeterminate dendritic cell tumor (IDCT) is rare histiocytic tumor characterized by the proliferation of indeterminate dendritic cells. It is more often diagnosed in middle-aged people, in approximately equal proportions in men and women. The etiology of IDCT is unknown. Differential diagnosis is carried out with other diseases that mimic IDCT and is important for determining treatment tactics. The present paper presents a clinical case of IDCT in a 48-year-old man. Using only the patient's complaints and examination data was not enough to diagnose the disease. The similarity of skin manifestations in IDCT with other skin pathologies requires an immunohistochemical study of the affected areas for CD1a, CD68, S100, Langerin expression evaluation as well as the presence of Birbeck's granules visulization. Routine histological examination does not sufficient for correct IDCT diagnostics.\",\"PeriodicalId\":23618,\"journal\":{\"name\":\"Vestnik dermatologii i venerologii\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-09-06\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Vestnik dermatologii i venerologii\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.25208/vdv8137\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q4\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Vestnik dermatologii i venerologii","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.25208/vdv8137","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q4","JCRName":"Medicine","Score":null,"Total":0}
Indeterminate dendritic cell tumor (IDCT) is rare histiocytic tumor characterized by the proliferation of indeterminate dendritic cells. It is more often diagnosed in middle-aged people, in approximately equal proportions in men and women. The etiology of IDCT is unknown. Differential diagnosis is carried out with other diseases that mimic IDCT and is important for determining treatment tactics. The present paper presents a clinical case of IDCT in a 48-year-old man. Using only the patient's complaints and examination data was not enough to diagnose the disease. The similarity of skin manifestations in IDCT with other skin pathologies requires an immunohistochemical study of the affected areas for CD1a, CD68, S100, Langerin expression evaluation as well as the presence of Birbeck's granules visulization. Routine histological examination does not sufficient for correct IDCT diagnostics.