SARS-CoV-2致迟发性新生儿脑膜炎1例

IF 0.5 Q4 PEDIATRICS

Archives of Pediatric Infectious Diseases Pub Date : 2021-08-09 DOI:10.5812/pedinfect.113879

Z. Jamali, Fatemeh Dehghani, A. Hosseininasab

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引用次数: 1

摘要

引言：严重急性呼吸系统综合征冠状病毒-19感染的中枢神经系统在新生儿中似乎非常罕见。我们报告了伊朗东南部克尔曼·阿夫扎利普尔医院收治的一名新生儿的病毒性脑膜炎病例。病例介绍：患者是一名15天大的新生儿，入院前一天出现嗜睡、发烧和进食不良。在初步评估和实验治疗后，通过脑脊液聚合酶链式反应（PCR）分析，病毒性脑膜炎被诊断为严重急性呼吸系统综合征冠状病毒19型。经验性治疗采用抗生素和支持性护理。病毒性脑膜炎确诊后，停止使用抗生素。在两周后的随访中，新生儿情况良好，没有特别的问题。结论：本报告为一起新生儿严重急性呼吸系统综合征冠状病毒2型脑膜炎病例。因此，如果有流行病学证据，新生儿也应考虑这种病毒引起的中枢神经系统受累。

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A Case Report of Late-Onset Neonatal Meningitis Caused by SARS-CoV-2

Introduction: Central nervous system involvement by SARS-CoV-19 appears to be very rare in neonates. We report a case of viral meningitis in a neonate admitted to Kerman Afzalipour Hospital in Southeastern Iran. Case Presentation: The patient was a 15-day-old neonate who presented with lethargy, fever, and poor feeding the day before admission. After the initial evaluation and experimental treatment, viral meningitis was diagnosed with SARS- CoV-19 by polymerase chain reaction (PCR) analysis of cerebrospinal fluid. Empirical treatment was done with antibiotics and supportive care. After viral meningitis was confirmed, the antibiotics were discontinued. In a follow-up two weeks later, the neonate had a good condition with no particular problem. Conclusions: This report is a case of SARS-CoV-2 meningitis in a neonate. Therefore, if there is epidemiological evidence, the central nervous system involvement due to this virus should also be considered in neonates.

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来源期刊

Archives of Pediatric Infectious Diseases PEDIATRICS-

CiteScore

1.80

自引率

14.30%

发文量

期刊介绍： Archives Of Pediatric Infectious Disease is a clinical journal which is informative to all practitioners like pediatric infectious disease specialists and internists. This authoritative clinical journal was founded by Professor Abdollah Karimi in 2012. The Journal context is devoted to the particular compilation of the latest worldwide and interdisciplinary approach and findings including original manuscripts, meta-analyses and reviews, health economic papers, debates and consensus statements of clinical relevance to pediatric disease field, especially infectious diseases. In addition, consensus evidential reports not only highlight the new observations, original research and results accompanied by innovative treatments and all the other relevant topics but also include highlighting disease mechanisms or important clinical observations and letters on articles published in the journal.