手指皱纹扫描量化交感神经功能的适用性

IF 2 Q3 NEUROSCIENCES

Clinical Neurophysiology Practice Pub Date : 2022-01-01 DOI:10.1016/j.cnp.2022.03.005

Maurice Sopacua , Carla M.L. Gorissen-Brouwers , Bianca T.A. de Greef , Isis B.T. Joosten , Catharina G. Faber , Ingemar S.J. Merkies , Janneke G.J. Hoeijmakers

{"title":"手指皱纹扫描量化交感神经功能的适用性","authors":"Maurice Sopacua , Carla M.L. Gorissen-Brouwers , Bianca T.A. de Greef , Isis B.T. Joosten , Catharina G. Faber , Ingemar S.J. Merkies , Janneke G.J. Hoeijmakers","doi":"10.1016/j.cnp.2022.03.005","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><p>Stimulated skin wrinkling test (SSW) has been launched as a non-invasive diagnostic procedure. However, no normative age dependent values have been reported that can be applied in clinical practice. The objectives of the study were to (1) collect age-dependent normative values according to the 5-point scale assessment for the SSW, to (2) determine reliability scores for the obtained norm values, and to (3) introduce a new digital method for SSW assessment, the Digit Wrinkle Scan© (DWS©) for detection of wrinkles in a more quantitative manner.</p></div><div><h3>Methods</h3><p>Firstly, 82 healthy participants were included, divided in 5 age groups. The participants underwent SSW using lidocaine and prilocaine topical cream. Secondly, 35 healthy participants were included to test whether the DWS© could be a novel manner to assess the grade of wrinkling quantitatively. We determined the inter-observer reliability of both methods. Also, the intra-observer reliability was calculated for the DWS©.</p></div><div><h3>Results</h3><p>We found a decrease in normative values over age. The inter-observer reliability of assessment by the 5-point scale method was moderate after SSW (Cohen’s k: 0.53). Results of the DWS© indicate that total wrinkle length per mm<sup>2</sup> showed moderate to good agreement for the 4th and 5th digits after SSW, and a low agreement for the other digits.</p></div><div><h3>Conclusions</h3><p>Age-dependent normative values were obtained according to the 5-point scale, but its clinical application is doubtful since we found a moderate inter-observer reliability. We introduced the DWS© as a possible new method in order to quantify the grade of wrinkling.</p></div><div><h3>Significance</h3><p>We found unsatisfactory reliability scores, which hampers its usefulness for clinical practice.</p></div>","PeriodicalId":45697,"journal":{"name":"Clinical Neurophysiology Practice","volume":"7 ","pages":"Pages 115-119"},"PeriodicalIF":2.0000,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.sciencedirect.com/science/article/pii/S2467981X22000166/pdfft?md5=740eaf513be03da04dd05b87a250203d&pid=1-s2.0-S2467981X22000166-main.pdf","citationCount":"1","resultStr":"{\"title\":\"The applicability of the digit wrinkle scan to quantify sympathetic nerve function\",\"authors\":\"Maurice Sopacua , Carla M.L. Gorissen-Brouwers , Bianca T.A. de Greef , Isis B.T. Joosten , Catharina G. Faber , Ingemar S.J. Merkies , Janneke G.J. Hoeijmakers\",\"doi\":\"10.1016/j.cnp.2022.03.005\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objective</h3><p>Stimulated skin wrinkling test (SSW) has been launched as a non-invasive diagnostic procedure. However, no normative age dependent values have been reported that can be applied in clinical practice. The objectives of the study were to (1) collect age-dependent normative values according to the 5-point scale assessment for the SSW, to (2) determine reliability scores for the obtained norm values, and to (3) introduce a new digital method for SSW assessment, the Digit Wrinkle Scan© (DWS©) for detection of wrinkles in a more quantitative manner.</p></div><div><h3>Methods</h3><p>Firstly, 82 healthy participants were included, divided in 5 age groups. The participants underwent SSW using lidocaine and prilocaine topical cream. Secondly, 35 healthy participants were included to test whether the DWS© could be a novel manner to assess the grade of wrinkling quantitatively. We determined the inter-observer reliability of both methods. Also, the intra-observer reliability was calculated for the DWS©.</p></div><div><h3>Results</h3><p>We found a decrease in normative values over age. The inter-observer reliability of assessment by the 5-point scale method was moderate after SSW (Cohen’s k: 0.53). Results of the DWS© indicate that total wrinkle length per mm<sup>2</sup> showed moderate to good agreement for the 4th and 5th digits after SSW, and a low agreement for the other digits.</p></div><div><h3>Conclusions</h3><p>Age-dependent normative values were obtained according to the 5-point scale, but its clinical application is doubtful since we found a moderate inter-observer reliability. We introduced the DWS© as a possible new method in order to quantify the grade of wrinkling.</p></div><div><h3>Significance</h3><p>We found unsatisfactory reliability scores, which hampers its usefulness for clinical practice.</p></div>\",\"PeriodicalId\":45697,\"journal\":{\"name\":\"Clinical Neurophysiology Practice\",\"volume\":\"7 \",\"pages\":\"Pages 115-119\"},\"PeriodicalIF\":2.0000,\"publicationDate\":\"2022-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.sciencedirect.com/science/article/pii/S2467981X22000166/pdfft?md5=740eaf513be03da04dd05b87a250203d&pid=1-s2.0-S2467981X22000166-main.pdf\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Clinical Neurophysiology Practice\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S2467981X22000166\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"NEUROSCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Clinical Neurophysiology Practice","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S2467981X22000166","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"NEUROSCIENCES","Score":null,"Total":0}

引用次数: 1

摘要

目的:模拟皮肤起皱试验(SSW)作为一种非侵入性的诊断方法已被推出。然而，没有规范的年龄依赖值可用于临床实践的报道。本研究的目的是:(1)根据5分制的SSW评估收集年龄相关的规范值;(2)确定获得的规范值的可靠性评分;(3)引入一种新的数字SSW评估方法，即数字皱纹扫描©(DWS©)，以更定量的方式检测皱纹。方法首先选取健康受试者82例，分为5个年龄组。参与者使用利多卡因和丙胺卡因局部乳膏进行SSW。其次，选取35名健康被试，检验DWS©是否可以作为一种新的定量评估起皱程度的方法。我们确定了两种方法的观察者间信度。同时，计算了DWS©的观察者内信度。结果我们发现，随着年龄的增长，正常值有所下降。SSW后5点量表法评估的观察者间信度为中等(Cohen’s k: 0.53)。DWS©结果表明，SSW后的第4和第5指的总皱纹长度每mm2的一致性中等至良好，而其他手指的一致性较低。结论根据5分制获得了与年龄相关的规范值，但由于我们发现观察者间的信度适中，因此其临床应用值得怀疑。我们引入了DWS©作为一种量化起皱程度的新方法。我们发现信度评分不令人满意，这阻碍了其在临床实践中的应用。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

The applicability of the digit wrinkle scan to quantify sympathetic nerve function

Objective

Stimulated skin wrinkling test (SSW) has been launched as a non-invasive diagnostic procedure. However, no normative age dependent values have been reported that can be applied in clinical practice. The objectives of the study were to (1) collect age-dependent normative values according to the 5-point scale assessment for the SSW, to (2) determine reliability scores for the obtained norm values, and to (3) introduce a new digital method for SSW assessment, the Digit Wrinkle Scan© (DWS©) for detection of wrinkles in a more quantitative manner.

Methods

Firstly, 82 healthy participants were included, divided in 5 age groups. The participants underwent SSW using lidocaine and prilocaine topical cream. Secondly, 35 healthy participants were included to test whether the DWS© could be a novel manner to assess the grade of wrinkling quantitatively. We determined the inter-observer reliability of both methods. Also, the intra-observer reliability was calculated for the DWS©.

Results

We found a decrease in normative values over age. The inter-observer reliability of assessment by the 5-point scale method was moderate after SSW (Cohen’s k: 0.53). Results of the DWS© indicate that total wrinkle length per mm² showed moderate to good agreement for the 4th and 5th digits after SSW, and a low agreement for the other digits.

Conclusions

Age-dependent normative values were obtained according to the 5-point scale, but its clinical application is doubtful since we found a moderate inter-observer reliability. We introduced the DWS© as a possible new method in order to quantify the grade of wrinkling.

Significance

We found unsatisfactory reliability scores, which hampers its usefulness for clinical practice.

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

Clinical Neurophysiology Practice NEUROSCIENCES-

CiteScore

3.90

自引率

0.00%

发文量

审稿时长

71 days

期刊介绍： Clinical Neurophysiology Practice (CNP) is a new Open Access journal that focuses on clinical practice issues in clinical neurophysiology including relevant new research, case reports or clinical series, normal values and didactic reviews. It is an official journal of the International Federation of Clinical Neurophysiology and complements Clinical Neurophysiology which focuses on innovative research in the specialty. It has a role in supporting established clinical practice, and an educational role for trainees, technicians and practitioners.