血清IL-7浓度与银屑病发病关系的病例对照研究:安培系统回顾与荟萃分析

IF 0.6 4区医学 Q4 IMMUNOLOGY

European Journal of Inflammation Pub Date : 2023-04-07 DOI:10.1177/1721727x231160361

Jiandong Liu, Linxi Zeng, Xin Huang, Lu Liu, Nana Guo, Jinfang Zhang, G. Zhang

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引用次数: 0

摘要

探讨血清IL-17浓度与银屑病发病机制的关系。通过文献检索建立amper数据库，并采用meta分析对纳入文献的效果指标进行评价。研究中包括5篇文章，根据纽卡斯尔-渥太华量表（NOS）标准，质量评估得分为6-7分。两组间的标准化平均差（SMD）存在异质性（I2=98.63%）。随机效应模型分析显示，组合SMD=2.11，95%CI（0.79，3.43），研究之间的效应大小具有统计学意义（z=3.13，p=0.00）。病例组和对照组之间的血清IL-17浓度存在统计学差异。病例组血清IL-17浓度明显高于对照组。

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The case-control study on relationship between the serum concentration of IL-7 and the pathogenesis of psoriasis: ampere systematic review and meta-Analysis

To explore the relationship between the serum concentration of IL-17 and the pathogenesis of psoriasis. ampere database was established through literature search, and meta-analysis was used to evaluate the effect indicator of the included literatures. 5 articles were included in the study, and the quality evaluation score was 6–7 points by the Newcastle-Ottawa Scale (NOS) criteria. There was heterogeneity in the standardized mean difference (SMD) between the two groups (I2 = 98.63%). The random effect model analysis showed that the combined SMD = 2.11, 95%CI (0.79, 3.43), the effect size between studies was statistically significant (z = 3.13, p = 0.00). There was a statistical difference in serum IL-17 concentration between the case group and the control group. The serum concentration of IL-17 in the case group was higher than that in the control group.

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来源期刊

European Journal of Inflammation 医学-免疫学

CiteScore

0.90

自引率

0.00%

发文量

审稿时长

15 weeks

期刊介绍： European Journal of Inflammation is a multidisciplinary, peer-reviewed, open access journal covering a wide range of topics in inflammation, including immunology, pathology, pharmacology and related general experimental and clinical research.