{"title":"室温下用天然存在的Mandelic酸作为高效有机催化剂在乙醇水溶液中合成3,3-双（吲哚-3-基）吲哚-2-酮、双（吲哚3-基）（芳基）甲烷和三（吲哚-3基）甲烷的通用方法","authors":"A. Singh, G. Kaur, A. Kaur, V. Gupta, B. Banerjee","doi":"10.2174/2213346107666200228125715","DOIUrl":null,"url":null,"abstract":"A simple, facile, straightforward and environmentally benign protocol has been developed for the efficient synthesis of pharmaceutically interesting 3,3-bis(indol-3-yl)indolin-2-ones, bis(indol- 3-yl)(aryl)methanes and tris(indol-3-yl)methanes using a catalytic amount of mandelic acid as an efficient, naturally occurring, low-cost, commercially available organo-catalyst in aqueous ethanol at room temperature.","PeriodicalId":10856,"journal":{"name":"Current Green Chemistry","volume":null,"pages":null},"PeriodicalIF":1.1000,"publicationDate":"2020-03-31","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"13","resultStr":"{\"title\":\"A General Method for the Synthesis of 3,3-bis(indol-3-yl)indolin-2-ones, bis(indol-3-yl)(aryl)methanes and tris(indol-3-yl)methanes Using Naturally Occurring Mandelic Acid as an Efficient Organo-catalyst in Aqueous Ethanol at Room Temperature\",\"authors\":\"A. Singh, G. Kaur, A. Kaur, V. Gupta, B. Banerjee\",\"doi\":\"10.2174/2213346107666200228125715\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"A simple, facile, straightforward and environmentally benign protocol has been developed for the efficient synthesis of pharmaceutically interesting 3,3-bis(indol-3-yl)indolin-2-ones, bis(indol- 3-yl)(aryl)methanes and tris(indol-3-yl)methanes using a catalytic amount of mandelic acid as an efficient, naturally occurring, low-cost, commercially available organo-catalyst in aqueous ethanol at room temperature.\",\"PeriodicalId\":10856,\"journal\":{\"name\":\"Current Green Chemistry\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":1.1000,\"publicationDate\":\"2020-03-31\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"13\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Current Green Chemistry\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.2174/2213346107666200228125715\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Current Green Chemistry","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.2174/2213346107666200228125715","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
A General Method for the Synthesis of 3,3-bis(indol-3-yl)indolin-2-ones, bis(indol-3-yl)(aryl)methanes and tris(indol-3-yl)methanes Using Naturally Occurring Mandelic Acid as an Efficient Organo-catalyst in Aqueous Ethanol at Room Temperature
A simple, facile, straightforward and environmentally benign protocol has been developed for the efficient synthesis of pharmaceutically interesting 3,3-bis(indol-3-yl)indolin-2-ones, bis(indol- 3-yl)(aryl)methanes and tris(indol-3-yl)methanes using a catalytic amount of mandelic acid as an efficient, naturally occurring, low-cost, commercially available organo-catalyst in aqueous ethanol at room temperature.
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