印度北部喜马偕尔邦康格拉地区婆罗门和拉杰普特人群中人类特异性Alu InDel多态性分布

Pub Date : 2021-08-05 DOI:10.31901/24566330.2021/21.03.784
S. Chahal
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引用次数: 0

摘要

摘要采用ACE、APO、PV92、CD4、PLAT和TPA25等6个常染色体Alu-InDel(插入/缺失)标记,对印度北部喜马偕尔邦Kangra区的两个内配种姓群体Brahmin(n=250)和Rajput(n=250。除了Rajput中的Alu APO和PV92外,其他标记的基因型频率在两个群体中都处于Hardy-Weinberg平衡。Brahmin(0.4134)的平均杂合度(H)高于Rajput(0.3809),二者之间的基因分化程度较低(GST=0.00898)。遗传距离分析显示,目前Rajput群体与该地区早期报道的Gaddi-Rajput和Gaddi-Brahmin群体具有密切的遗传亲缘关系,但目前的Brahmin人群被发现离他们很远。
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Distribution of Human-specific Alu InDel Polymorphisms in the Brahmin and Rajput Populations of Kangra District of Himachal Pradesh, North India
ABSTRACT The genetic constitution of two endogamous caste populations viz., the Brahmin (n=250) and Rajput (n=250) of Kangra district of the North Indian state of Himachal Pradesh was studied using six autosomal Alu InDel (insertion/deletion) markers viz., ACE, APO, PV92, CD4, PLAT, and TPA25 All markers were found to be polymorphic. Except for Alu APO and PV92 in the Rajput, genotype frequencies of other markers were in the Hardy-Weinberg equilibrium in both the populations. The average heterozygosity (H) was observed higher in the Brahmin (0.4134) compared to the Rajput (0.3809) and the degree of genic differentiation was low between them (GST =0.00898). The genetic distance analysis revealed close genetic affinities of the present Rajput population with the Gaddi Rajput and Gaddi Brahmin populations reported earlier from the district but the present Brahmin population was found distant from them.
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