“社会生物学”:社会经济因素如何影响肠道微生物群并增强病理易感性?-小型评论

J. Nobre, D. Alpuim Costa
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引用次数: 3

摘要

肠道菌群被公认为是健康和疾病的关键决定因素。因此,一些研究集中在因果关系和微生物群在多种疾病中的预测/预后价值上。然而,更重要的是要了解是什么引发了微生物群的变化,以及这些变化如何导致对疾病的易感性增加。一些研究已经证明,肠道微生物群可能会因生活方式而改变,从而导致病理。如果社会经济因素也会影响肠道菌群组成,从而增加对疾病的易感性,那该怎么办?也许,这是造成社会经济地位较高和较低的人在健康方面的不平等加剧的因素之一。在这篇综述中,我们旨在了解更多关于这一主题和“社会生物群落”的真正影响。此外,我们提出了减轻这些因素对肠道微生物群组成影响的措施。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
”Sociobiome”: How do socioeconomic factors influence gut microbiota and enhance pathology susceptibility? - A mini-review
The gut microbiota is becoming well recognized as a key determinant of health and disease. As a result, several studies have focused on causality and the predictive/prognostic value of the microbiota in a wide range of diseases. However, it is of greater importance to understand what sparks changes in the microbiota and how these alterations contribute to an increased susceptibility to disease. A few studies have already demonstrated that the gut microbiota could be modified by lifestyle, consequently leading to pathology. What if socioeconomic factors can also impact the gut microbiota composition and, thus, increase the susceptibility to disease? Perhaps, this is one of the factors that may have contributed to the increased inequalities between people with higher and lower socioeconomic status in terms of health. In this review, we aimed to understand more about this topic and the real impact of the “sociobiome.” Furthermore, we proposed measures to mitigate the impact of these factors on the gut microbiota composition.
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