Yasaman Rafiee, Benedict C. Jones, Victor Shiramizu
{"title":"当孕酮水平高时，对病原体的厌恶感是否会增加?使用估计孕酮水平的受试者间研究证据","authors":"Yasaman Rafiee, Benedict C. Jones, Victor Shiramizu","doi":"10.1007/s40750-022-00208-5","DOIUrl":null,"url":null,"abstract":"<div><h3>Objective</h3><p>The Compensatory Prophylaxis Hypothesis proposes that women will show increased pathogen disgust at points in the menstrual cycle when progesterone is high, compensating for the immunosuppressive effects of progesterone. However, evidence for the Compensatory Prophylaxis Hypothesis from studies that used longitudinal designs to investigate whether pathogen disgust tracks changes in progesterone is mixed. It was recently proposed that longitudinal designs may be poorly suited to testing the Compensatory Prophylaxis Hypothesis because carry-over effects when women are tested repeatedly in within-subject designs might obscure the effects of progesterone and pathogen disgust. Consequently, we used a between-subjects design to test for a positive relationship between scores on the pathogen disgust subscale of the Three Domain Disgust Scale and progesterone levels imputed from menstrual cycle data using actuarial tables.</p><h3>Methods</h3><p>We employed a between-subject design on <i>N = 1346</i> women using the Three Domains of Disgust Scale (TDDS).</p><h3>Results</h3><p>We found no evidence for a positive effect of progesterone on pathogen disgust, suggesting that null results for the hypothesized relationship between progesterone and pathogen disgust are not limited to studies using designs that may be subject to carry-over effects caused by repeated testing.</p><h3>Conclusion</h3><p>Our results add to a growing body of research that does not support the Compensatory Prophylaxis Hypothesis.</p></div>","PeriodicalId":1,"journal":{"name":"Accounts of Chemical Research","volume":null,"pages":null},"PeriodicalIF":16.4000,"publicationDate":"2022-12-27","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://link.springer.com/content/pdf/10.1007/s40750-022-00208-5.pdf","citationCount":"2","resultStr":"{\"title\":\"Is Pathogen Disgust Increased on Days of the Menstrual Cycle when Progesterone is High? Evidence from a Between-Subjects Study Using Estimated Progesterone Levels\",\"authors\":\"Yasaman Rafiee, Benedict C. Jones, Victor Shiramizu\",\"doi\":\"10.1007/s40750-022-00208-5\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Objective</h3><p>The Compensatory Prophylaxis Hypothesis proposes that women will show increased pathogen disgust at points in the menstrual cycle when progesterone is high, compensating for the immunosuppressive effects of progesterone. However, evidence for the Compensatory Prophylaxis Hypothesis from studies that used longitudinal designs to investigate whether pathogen disgust tracks changes in progesterone is mixed. It was recently proposed that longitudinal designs may be poorly suited to testing the Compensatory Prophylaxis Hypothesis because carry-over effects when women are tested repeatedly in within-subject designs might obscure the effects of progesterone and pathogen disgust. Consequently, we used a between-subjects design to test for a positive relationship between scores on the pathogen disgust subscale of the Three Domain Disgust Scale and progesterone levels imputed from menstrual cycle data using actuarial tables.</p><h3>Methods</h3><p>We employed a between-subject design on <i>N = 1346</i> women using the Three Domains of Disgust Scale (TDDS).</p><h3>Results</h3><p>We found no evidence for a positive effect of progesterone on pathogen disgust, suggesting that null results for the hypothesized relationship between progesterone and pathogen disgust are not limited to studies using designs that may be subject to carry-over effects caused by repeated testing.</p><h3>Conclusion</h3><p>Our results add to a growing body of research that does not support the Compensatory Prophylaxis Hypothesis.</p></div>\",\"PeriodicalId\":1,\"journal\":{\"name\":\"Accounts of Chemical Research\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":16.4000,\"publicationDate\":\"2022-12-27\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://link.springer.com/content/pdf/10.1007/s40750-022-00208-5.pdf\",\"citationCount\":\"2\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Accounts of Chemical Research\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://link.springer.com/article/10.1007/s40750-022-00208-5\",\"RegionNum\":1,\"RegionCategory\":\"化学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"CHEMISTRY, MULTIDISCIPLINARY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Accounts of Chemical Research","FirstCategoryId":"1085","ListUrlMain":"https://link.springer.com/article/10.1007/s40750-022-00208-5","RegionNum":1,"RegionCategory":"化学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"CHEMISTRY, MULTIDISCIPLINARY","Score":null,"Total":0}
Is Pathogen Disgust Increased on Days of the Menstrual Cycle when Progesterone is High? Evidence from a Between-Subjects Study Using Estimated Progesterone Levels
Objective
The Compensatory Prophylaxis Hypothesis proposes that women will show increased pathogen disgust at points in the menstrual cycle when progesterone is high, compensating for the immunosuppressive effects of progesterone. However, evidence for the Compensatory Prophylaxis Hypothesis from studies that used longitudinal designs to investigate whether pathogen disgust tracks changes in progesterone is mixed. It was recently proposed that longitudinal designs may be poorly suited to testing the Compensatory Prophylaxis Hypothesis because carry-over effects when women are tested repeatedly in within-subject designs might obscure the effects of progesterone and pathogen disgust. Consequently, we used a between-subjects design to test for a positive relationship between scores on the pathogen disgust subscale of the Three Domain Disgust Scale and progesterone levels imputed from menstrual cycle data using actuarial tables.
Methods
We employed a between-subject design on N = 1346 women using the Three Domains of Disgust Scale (TDDS).
Results
We found no evidence for a positive effect of progesterone on pathogen disgust, suggesting that null results for the hypothesized relationship between progesterone and pathogen disgust are not limited to studies using designs that may be subject to carry-over effects caused by repeated testing.
Conclusion
Our results add to a growing body of research that does not support the Compensatory Prophylaxis Hypothesis.
期刊介绍：
Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance.
Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.
求助内容：
应助结果提醒方式：
京公网安备 11010802042870号
