新生儿狼疮综合征并发室性心动过速1例报告

Q4 Medicine

中华实用儿科临床杂志 Pub Date : 2020-03-30 DOI:10.3760/CMA.J.CN101070-20200316-00423

Zhongjian Wang, Nan Wang, Lin Wang, R. Jin

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引用次数: 0

摘要

A retrospective analysis was conducted on the clinical data of a case of neonatal lupus syndrome with ventricular tachycardia and developmental abnormalities admitted to the Pediatrics Department of Tongji Medical College Affiliated Union Hospital, Huazhong University of Science and Technology. Child, female, 3 days; The clinical features include ventricular arrhythmia, rash, jaundice, and developmental abnormalities; Physical examination: Fast pulse rate, yellow stained skin, wide eye distance, epicanthus, high nasal bridge, right side through palm; Anti Sjogren's syndrome antigen A (SSA) antibodies and anti Ro-52 antibodies are positive. The electrocardiogram shows paroxysmal ventricular tachycardia (accompanied by ventricular atrial retrograde transmission), and chromosome karyotype analysis shows 46, XX. Provide treatment such as electrocardiographic monitoring, anti arrhythmia, anti infection, protection of heart function, immunoglobulin therapy, and jaundice treatment. After 11 days of hospitalization, the condition improved and was discharged; Regularly follow up until 8 months of birth, and the child can recover. The clinical manifestations of neonatal lupus syndrome are atypical, with prominent cardiac damage. In addition to heart conduction block, it may also lead to other arrhythmias, such as ventricular tachycardia.

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Case report of neonatal lupus syndrome with ventricular tachycardia

对华中科技大学同济医学院附属协和医院儿科收治的1例新生儿狼疮综合征并室性心动过速伴发育异常患儿的临床资料进行回顾性分析。患儿，女，3 d；临床特点为室性心律失常、皮疹、黄疸、发育异常；查体：脉率快，皮肤黄染，宽眼距、内眦赘皮、高鼻梁，右侧通贯掌；抗干燥综合征抗原A(SSA)抗体、抗Ro-52抗体阳性，心电图示阵发性室性心动过速(伴室房逆传)，染色体核型分析示46，XX。予心电监护、抗心律失常、抗感染、保护心功能、免疫球蛋白、退黄等治疗，住院11 d后病情好转出院；定期随访至出生8个月，患儿恢复可。新生儿狼疮综合征临床表现不典型，心脏损害较为突出，除心脏传导阻滞外，也可能导致其他心律失常，如室性心动过速。

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来源期刊

中华实用儿科临床杂志 Medicine-Pediatrics, Perinatology and Child Health

CiteScore

0.60

自引率

0.00%

发文量

14243

期刊介绍： Chinese Journal of Applied Clinical Pediatrics ( semi-monthly ) is a core journal of paediatrics under the supervision of China Association for Science and Technology, sponsored by Chinese Medical Association and undertaken by Xinxiang Medical College. Founded in 1986, it is openly circulated both at home and abroad. The journal has several columns, such as Expert Forum, Experimental Research and Paediatric Surgery, which are mainly for paediatric medical workers and medical researchers in hospitals. Its purpose is to reflect the new theories and technologies in paediatric medicine and scientific research at home and abroad, and to promote academic exchanges. Chinese Journal of Applied Clinical Pediatrics is a source journal of China Science Citation Database (CSCD), a core journal of Peking University, a source journal of Chinese science and technology paper statistics (China Science and Technology Core Journals), a core academic journal of RCCSE, a high-quality scientific and technical journal of China, a high-quality scientific and technical journal of China Association for Science and Technology, and a high-quality scientific and technical journal of China Biomedical Science and Technology Association. We have been published in China Biomedical Literature Database (SinoMed), China Knowledge Network, Wanfang Data Knowledge Service Platform, China Academic Journal Abstracts, Scopus Database, Chemical Abstracts (USA), Japan Science and Technology Agency (JSTA) Database, Copernicus Abstracts (Poland), Abstracts of the Centre for Agricultural and Biological Sciences (CABS) of the United Kingdom, Cambridge Scientific Abstracts ProQuest Database, WHO Medical Journal of the Western Pacific Region (WMPR), and WHO Medical Journal of the Western Pacific Region (WMPR) of the United States. We have been included in dozens of authoritative databases at home and abroad, such as WHO Western Pacific Region Index of Medicine (WPRIM), Ullrich's Guide to Periodicals, and so on.