西酞普兰——SSRI抗抑郁药被重新发现

Q4 Medicine

Psychiatria Pub Date : 2020-08-30 DOI:10.5603/psych.2020.0020

A. Czernikiewicz, Tomasz Horoch

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引用次数: 0

摘要

西酞普兰是选择性5 -羟色胺再摄取抑制剂(SSRIs)中最具选择性的分子，其活性对映体s -西酞普兰除外。它属于抗抑郁和抗焦虑药物，是目前治疗伴有惊恐发作的抑郁症和焦虑症的标准药物，尤其适用于老年人。与其他药物发生不良反应的风险较低，因为西酞普兰被几种CYP同工酶代谢。与其他ssri类药物相比，西酞普兰引起性功能障碍的风险似乎相对较小。

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Citalopram ― lek antydepresyjny z grupy SSRI odkryty na nowo

Citalopram is the most selective molecule in the class of selective serotonin reuptake inhibitors (SSRIs), except its active enantiomer S-citalopram. It belongs to the group of antidepressant and anxiolytic drugs, which is currently the standard in the treatment of depressive disorders and anxiety disorders with panic attacks, especially for the elderly. There is a lower risk of adverse interactions with other drugs because citalopram is metabolized by several CYP isoenzymes. The risk of sexual dysfunction caused by citalopram appears to be relatively smaller in comparison with other SSRIs.

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来源期刊

Psychiatria Medicine-Psychiatry and Mental Health

CiteScore

0.60

自引率

0.00%

发文量

期刊介绍： "Psychiatry" is a quaternary journal addressed to professionals coming from all branches of psychiatry practicing in both hospital and outpatients departments. "Psychiatry" issues original articles, reviews, case reports, commentaries, and translated articles from leading journals in the field of psychiatry. The papers are reviewed by the members of the editorial board. "Psychiatry" also publishes the practice guidelines in sexology. Psychopharmacotherapy is the main field of interests of the quatrernary.