牛奶酪蛋白的结构与生物学功能

IF 0.2 Q4 MEDICINE, GENERAL & INTERNAL
S. Petrova, S. Khlgatian, O. Emelyanova, L. A. Pishchulina, V. Berzhets
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引用次数: 0

摘要

牛奶中含有酪蛋白,在成人和儿童过敏反应临床症状的发展中起着重要作用。到目前为止,已经对酪蛋白的性质进行了研究,并确定了其主要结构。然而,尽管有可用的科学评论和原创文章,牛奶酪蛋白胶束的结构组织及其生物功能的问题仍然非常有争议。在这方面,拟议的综述是相关的,因为它最充分地反映了关于各种类型酪蛋白及其理化和免疫生物学特性的最新信息,并详细分析了关于酪蛋白胶束结构组织的现有理论。我们的综述中特别感兴趣的是对母乳和牛奶中酪蛋白的结构和性质的比较分析数据,以及关于牛奶酪蛋白的致敏活性及其与其他哺乳动物物种的乳蛋白的交叉反应性的部分。这篇综述的目的是总结酪蛋白结构和特性的最新数据,并确定它们在乳制品致敏形成中的作用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Structure And Biological Functions Of Milk Caseins
Caseins, which are contained in milk, play a significant role in the development of clinical symptoms of allergic reactions in adults and children. To date, the properties of caseins have been studied, their primary structure has been identified. However, despite available scientific reviews and original articles, an issue of the structural organization of milk casein micelles and their biological functions is still very controversial. In this regard, the proposed review is relevant, since it most fully reflects current information about various types of caseins, their physicochemical and immunobiological properties, and analyzes in detail the existing theories on the structural organization of casein micelles. Of particular interest in our review are the data on the comparative analysis of the structure and properties of caseins in both human breast milk and cow’s milk, as well as the section dealing with the allergenic activity of cow’s milk caseins and their cross-reactivity with milk proteins of other mammalian species. The objective of this review is to summarize current data on the structure and properties of casein proteins, and to determine their role in the formation of sensitization to dairy products.
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来源期刊
Russian Open Medical Journal
Russian Open Medical Journal MEDICINE, GENERAL & INTERNAL-
CiteScore
0.90
自引率
0.00%
发文量
39
期刊介绍: Russian Open Medical Journal (RusOMJ) (ISSN 2304-3415) is an international peer reviewed open access e-journal. The website is updated quarterly with the RusOMJ’s latest original research, clinical studies, case reports, reviews, news, and comment articles. This Journal devoted to all field of medicine. All the RusOMJ’s articles are published in full on www.romj.org with open access and no limits on word counts. Our mission is to lead the debate on health and to engage, inform, and stimulate doctors, researchers, and other health professionals in ways that will improve outcomes for patients. The RusOMJ team is based mainly in Saratov (Russia), although we also have editors elsewhere in Russian and in other countries.
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