癌症利用宿主的共同形态发生源

A. N. Shoutko
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引用次数: 0

摘要

造血干细胞的营养特性可以影响恶性生长,而不是免疫控制。福利国家成年人口按年龄划分的体重年增长率被用作代谢和增殖组织活动的最常见标准,这些数据与同一国家不同年龄组恶性和躯体疾病的死亡率进行了比较。淋巴谱系中不同细胞群随年龄的生理退化率也与上述参数之间的相关性有关。癌症死亡率下降,60多个人群中发现的非恶性疾病死亡率上升,这些人群的淋巴细胞数量和质量更新的生理温度最低。缺乏原始淋巴细胞的胸腺体积和增殖活性降低了生理体重更新以及癌症死亡率,但提高了体细胞死亡率,这与抗癌免疫相反。淋巴生成系统与恶性肿瘤的关系的预防特征似乎比防御更现实。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Cancer Uses the Common Morphogenesis Source of the Host
Trophic properties of hematopoietic stem cells can influence the malignant growth alternatively to immune control. The annual growth of the body mass by age in adult populations of welfare countries used as the most common criterion of metabolic and proliferative tissue activity, and these data compared with death’ rate for malignant and somatic diseases in different age-groups of the same countries. The rate of physiologic involution of different cell populations in the lymphoid lineage by age also involved in correlations between the above parameters. A decrease in death rate for cancer and increase it’s for non-malignant diseases found in 60+ populations, which have the lowest physiological temp of renewal of lymphocytes number and mass of the body. The lack of both the thymus gland volume and proliferative activity of naive lymphocytes reduces physiological body mass renewal as well as the cancer death rate but enhances somatic death rate, opposing to anticancer immunity at large. A protumor character of the lymphopoietic system’s relation with malignancy seems more realistic than defending one.
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