Mohd. Kaleem Khan, Faiz Ahmad, A. Mahmood, Jamal Azmat
{"title":"胃管内磷化铝中毒并爆炸为罕见现象1例","authors":"Mohd. Kaleem Khan, Faiz Ahmad, A. Mahmood, Jamal Azmat","doi":"10.22038/APJMT.2020.41679.1264","DOIUrl":null,"url":null,"abstract":"Suicide by poisoning is the second most common cause of death by suicide (27.9%) as per The National Crime Records Bureau (NCRB) India in 2015.Aluminum phosphide (ALP) is the leading agricultural poison used to commit suicide as where its availability is not properly regulated. Aluminum phosphide (ALP) is a highly toxic solid fumigant pesticide, rodenticide and insecticide. It is commonly used as outdoor and indoor pesticide in developing countries like India, Pakistan, Srilanka and Iran because it is a cheap, effective, free from toxic residue and do not alter the viability of seeds. Aluminium Phosphide (ALP) is a highly toxic fumigant which is used commonly as an indoor pesticide in agriculture based industry for storage of grains. ALP on ingestion reacts with a gastric water and release phosphine gas, which is highly flammable, and very toxic in nature. Over the last few decades ALP has emerged as an agent of choice being used as suicidal poisoning in a country where it is readily available. The high mortality rate is due to severe mitochondrial dysfunction leading to disruption of cellular respiration, causing tissue hypoxia and organ dysfunction. Despite long research no specific antidote could be developed and the treatment remained supportive. Spontaneous ignition of phosphine (PH3) is a rare but very peculiar phenomenon reported in the case of aluminium phosphide poisoning. Here we share our experience in a case of phosphine (PH3) poisoning, which presented with spontaneous ignition and blast during treatment which caught the attention of local and national media in India,","PeriodicalId":30463,"journal":{"name":"Asia Pacific Journal of Medical Toxicology","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2020-04-09","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Aluminum Phosphide Poisoning and Blast in Gastric Tube a Rare Phenomenon- A Case Report\",\"authors\":\"Mohd. Kaleem Khan, Faiz Ahmad, A. 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Over the last few decades ALP has emerged as an agent of choice being used as suicidal poisoning in a country where it is readily available. The high mortality rate is due to severe mitochondrial dysfunction leading to disruption of cellular respiration, causing tissue hypoxia and organ dysfunction. Despite long research no specific antidote could be developed and the treatment remained supportive. Spontaneous ignition of phosphine (PH3) is a rare but very peculiar phenomenon reported in the case of aluminium phosphide poisoning. Here we share our experience in a case of phosphine (PH3) poisoning, which presented with spontaneous ignition and blast during treatment which caught the attention of local and national media in India,\",\"PeriodicalId\":30463,\"journal\":{\"name\":\"Asia Pacific Journal of Medical Toxicology\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2020-04-09\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Asia Pacific Journal of Medical Toxicology\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.22038/APJMT.2020.41679.1264\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Asia Pacific Journal of Medical Toxicology","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.22038/APJMT.2020.41679.1264","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Aluminum Phosphide Poisoning and Blast in Gastric Tube a Rare Phenomenon- A Case Report
Suicide by poisoning is the second most common cause of death by suicide (27.9%) as per The National Crime Records Bureau (NCRB) India in 2015.Aluminum phosphide (ALP) is the leading agricultural poison used to commit suicide as where its availability is not properly regulated. Aluminum phosphide (ALP) is a highly toxic solid fumigant pesticide, rodenticide and insecticide. It is commonly used as outdoor and indoor pesticide in developing countries like India, Pakistan, Srilanka and Iran because it is a cheap, effective, free from toxic residue and do not alter the viability of seeds. Aluminium Phosphide (ALP) is a highly toxic fumigant which is used commonly as an indoor pesticide in agriculture based industry for storage of grains. ALP on ingestion reacts with a gastric water and release phosphine gas, which is highly flammable, and very toxic in nature. Over the last few decades ALP has emerged as an agent of choice being used as suicidal poisoning in a country where it is readily available. The high mortality rate is due to severe mitochondrial dysfunction leading to disruption of cellular respiration, causing tissue hypoxia and organ dysfunction. Despite long research no specific antidote could be developed and the treatment remained supportive. Spontaneous ignition of phosphine (PH3) is a rare but very peculiar phenomenon reported in the case of aluminium phosphide poisoning. Here we share our experience in a case of phosphine (PH3) poisoning, which presented with spontaneous ignition and blast during treatment which caught the attention of local and national media in India,
期刊介绍:
Asia Pacific Journal of Medical Toxicology (APJMT) aims to expand the knowledge of medical toxicology and tries to provide reliable information in this field for medical and healthcare professionals. APJMT mainly focuses on research related to medical toxicology issues in the Asia Pacific region and publishes articles on clinical and epidemiological aspects of toxicology, poisonings emergency care, addiction, drug interactions and adverse effects. The journal accepts and welcomes high quality papers in the form of original articles and rarely review articles, case reports and scientific letters relevant to medical practice in toxicology.