以细菌超滤液的生物技术复合物形式的专门产品,用于选择性吸收内毒素和肠道微生物群的代谢纠正

V. Poznyakovsky, M. Zakharenko, A. Avstrievskikh, E. N. Zinov'eva
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引用次数: 0

摘要

人体的肠道菌群具有重要的调节功能。在研究过程中,以膳食补充剂的形式开发了一种生物技术复合体,其功能特性旨在调节肠道生物狭窄,抑制致病性和条件性致病性微生物群,以及开发微生物群的有用部分。该专用产品的定性和定量成分包括,mg/5.5g,花(可溶性膳食纤维)-1375(1238);二叉双歧杆菌-620、短双歧杆菌-600、德氏乳杆菌-500、珊瑚Hericium coralloides-242.5、弗氏丙酸杆菌-100;乳果糖(50%)-400;益生元后滤液Subizym-200;二氧化硅-30;endofulvin(Endofulin,腐殖酸)-9.62(7.5);壳聚糖-5;对氨基苯甲酸-2;烟酰胺(维生素B)-1.81(1.8);半胱氨酸-1.25;泛酸钙(维生素B)-0.654(0.6);核黄素(维生素B)-0.16。生产技术的一个创新特点是液体浓缩形式的膳食补充剂,它可以确保快速通过胃,保存活性成分,并有效地实现特定的功能特性。对质量和安全的感官、微生物和物理化学指标进行了研究,其结果使确定规定的特性和保质期成为可能——在0-25°C的温度和不超过60%的相对湿度下保质期为1年。所开发的复合物建议以5.5g浓缩物的量使用,每天3次;课程持续时间-1个月。该产品已通过ArtLife LLC(托木斯克)的生产测试。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Specialized product in the form of a biotechnological complex of bacterial metafiltrates for selective sorption of endotoxins and metabolic correction of intestinal microflora
The intestinal microflora of the human body performs vital regulatory functions. In the course of the study, a biotechnological complex has been developed in the form of dietary supplements, the functional properties of which are aimed at regulating the intestinal biocenosis, inhibiting pathogenic and conditionally pathogenic microflora, as well as developing a useful part of the microbiota. The qualitative and quantitative composition of the specialized product includes, mg/5.5 g, floration (soluble dietary fiber) - 1,375 (1,238); metafiltrates Bifidobacterium bifidum - 620, Bifidobacterium breve - 600, Lactobacillus delbrueckii - 500, Hericium coralloides - 242.5, Propionibacterium freudenreichii - 100; lactulose (50 %) - 400; postbiotic metafiltrate Subtizym - 200; silicon dioxide - 30; endofulvin (Endofulvin, humic acids) - 9.62 (7.5); chitosan - 5; para-aminobenzoic acid - 2; nicotinamide (vitamin B) - 1.81 (1.8); cysteine - 1.25; calcium pantothenate (vitamin B) - 0.654 (0.6); riboflavin (vitamin B) - 0.16. An innovative feature of the production technology is a liquid concentrated form of dietary supplements, which ensures rapid passage through the stomach, the preservation of active principles and the effectiveness of the implementation of specified functional properties. The organoleptic, microbiological and physicochemical indicators of quality and safety have been studied, the results of which make it possible to determine the regulated characteristics and shelf life - 1 year at the temperature of 0-25 °C, relative humidity of not more than 60 %. The developed complex is recommended for use in the amount of 5.5 g of concentrate 3 times a day; course duration - 1 month. The product has passed production tests at ArtLife LLC (Tomsk).
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