儿科抗生素:是福还是祸?

Q4 Medicine
R. Kaur, Rajwinder Kaur, Ashlin Varghese, Nidhi Garg, S. Arora
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引用次数: 0

摘要

抗生素在抗菌治疗中起着至关重要的作用。在儿童使用的所有药物中,最常用的是抗生素,也是目前治疗传染性疾病不可缺少的手段。几种类型的抗生素已被引入临床实践,以治疗微生物感染。减少抗生素的不必要使用是一项全球需求和优先事项。本文旨在更好地了解和理解早期使用抗生素的影响。本文重点介绍了儿童抗生素的正确使用,详细介绍了早期和不适当使用抗生素如何影响正常身体发育过程中的肠道微生物群,从而通过糖尿病、肥胖、新生儿、婴幼儿和发育中儿童尿路感染等感染的复发和耐药因素、剂量需求等方式影响代谢。本文还简要介绍了几种处于开发阶段的新抗生素、新上市的抗生素以及一些召回和退出市场的抗生素。这项研究将有助于未来的研究人员探索儿科抗生素使用的最新信息。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Antibiotics in Paediatrics: A Boon or a Bane?
Antibiotics play an essential role in antimicrobial therapy. Among all the medications in children, the most commonly prescribed therapy is antibiotics and is currently the indispensable means to cure transmissible diseases. Several categories of antibiotics have been introduced into clinical practice to treat microbial infections. Reducing the unnecessary use of antibiotics is a global need and priority. This article aims to provide better knowledge and understanding of the impact of the early use of antibiotics. This article highlights the proper use of antibiotics in children, detailing how early and inappropriate use of antibiotics affect the gut microbiome during normal body development and consequently affect the metabolic by way of diabetes mellitus, obesity, and recurrence of infections such as UTI and resistance factors in neonates, infant and developing child, dose requirement, etc. Several new antibiotics in their development stage, newly marketed antibiotics, some recalled and withdrawn from the market are also briefly discussed in this article. This study will help future researchers to explore the latest information about antibiotics used in paediatrics.
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来源期刊
Anti-Infective Agents
Anti-Infective Agents Pharmacology, Toxicology and Pharmaceutics-Pharmacology
CiteScore
1.50
自引率
0.00%
发文量
47
期刊介绍: Anti-Infective Agents publishes original research articles, full-length/mini reviews, drug clinical trial studies and guest edited issues on all the latest and outstanding developments on the medicinal chemistry, biology, pharmacology and use of anti-infective and anti-parasitic agents. The scope of the journal covers all pre-clinical and clinical research on antimicrobials, antibacterials, antiviral, antifungal, and antiparasitic agents. Anti-Infective Agents is an essential journal for all infectious disease researchers in industry, academia and the health services.
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