慢性阻塞性肺疾病患者6分钟步行试验和增量穿梭步行试验与气流阻塞严重程度的相关性

P. Tej, S. Kumar, G. Vishnukanth
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引用次数: 1

摘要

背景:6MWT和ISWT等实地行走测试是心肺疾病患者功能能力的常用指标。本研究旨在评估慢性阻塞性肺病患者6分钟步行距离(6MWD)和增量穿梭步行距离(ISWD)与气流阻塞严重程度(FEV1%)的相关性。目的:比较6分钟步行试验和递增穿梭步行试验与COPD患者气流阻塞严重程度的相关性。设置和设计:在三级护理中心进行的基于医院的前瞻性横断面研究。方法和材料:一百一十二(112)名经肺活量测定证实的COPD患者接受6MWT和ISWT。采用GOLD标准对COPD的诊断及其严重程度进行评估。对同一名患者进行6MWT和ISWT,间隔5–6小时,步行距离(6MWD和ISWD)与COPD(FEV1)的严重程度相关。使用统计分析:单因素方差分析比较6MWT和ISWT患者不同级别COPD的平均步行距离。Pearson相关分析将吸烟包年数和年龄与6MWD和ISWD相关。结果:对6MWT和ISWT中的平均步行距离进行了估计,并对四类GOLD分级进行了比较。基于6MWT和ISWT的步行距离,相应GOLD等级的研究对象之间没有统计学上的显著差异。然而,ISWD和支气管扩张后FEV1之间存在线性相关性。线性回归模型显示,在我们的研究中,ISWD是支气管扩张剂后FEV1的独立贡献者。结论:递增穿梭步行试验是一种具有递增性质的外起搏接近标准的试验,可作为FEV1的适当替代品,用于确定COPD患者气流阻塞的严重程度。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Correlation of six minute walk test and incremental shuttle walk test with severity of airflow obstruction in patients with chronic obstructive pulmonary disease
Context: The field walking tests like 6MWT and ISWT are commonly used indicators of functional capacity in patients with cardiopulmonary diseases. This study was designed to assess the correlation of six minute walk distance (6MWD) and incremental shuttle walk distance (ISWD) with the severity of airflow obstruction (FEV1%) in patients with chronic obstructive pulmonary disease. Aims: Comparison of correlation of six minute walk test and Incremental shuttle walk test with the severity of airflow obstruction in COPD patients.Settings and Design: Hospital-based prospective cross-sectional study in a tertiary care centre. Methods and Material: One hundred and twelve (112) spirometrically confirmed COPD patients underwent 6MWT and ISWT. The diagnosis of COPD and its severity was assessed by the GOLD criteria. 6MWT and ISWT were done on the same patient with a gap of 5–6 hours and the distance walked (6MWD and ISWD) was correlated with the severity of COPD (FEV1). Statistical Analysis Used: One way ANOVA to compare mean distance walked in 6MWT and ISWT with different grades of COPD. Pearson Correlation was done to correlate packyears of smoking and age with 6MWD and ISWD. Results: The mean distance walked in the 6MWT and ISWT was estimated and compared across the four categories of GOLD grading. There was no statistically significant difference between the study subjects of corresponding GOLD grades based on the distance walked in 6MWT and in ISWT. However, a linear correlation was depicted between ISWD and post-bronchodilator FEV1. A model of linear regression showed that ISWD was an independent contributor to post-bronchodilator FEV1 in our study. Conclusions: Incremental shuttle walk test, an externally paced near to standard test with its incremental nature, can be used as an appropriate surrogate for FEV1 in determining the severity of airflow obstruction in COPD patients.
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