单纯疱疹病毒性脑炎：文献综述

Q4 Medicine

Romanian Journal of Neurology/ Revista Romana de Neurologie Pub Date : 2021-12-31 DOI:10.37897/rjn.2021.4.5

E. Tedyanto, N. Susilawathi, Anak Agung Sagung Ngurah Indradewi

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引用次数: 0

摘要

单纯疱疹病毒性脑炎是一种由1型单纯疱疹病毒（HSV-1）或2型引起的感染，会引起神经系统问题。即使使用抗病毒药物，HSVE也与成人的显著发病率和死亡率有关，无论治疗如何，它都是婴儿和儿童的致命疾病。最可能的途径包括通过嗅觉或三叉神经的逆行传播，以及血行传播。最常见的症状是脑病、发烧、抽搐、头痛和局部神经功能障碍。需要准确的病史和体格检查来确定单纯疱疹病毒性脑炎（HSVE），并建议在确诊后立即进行评估。HSVE是一种可能致命的神经退行性疾病。对所有疑似或确诊病例进行快速诊断和早期诊断将导致早期开始静脉注射阿昔洛韦，这可能会降低发病率和死亡。

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查看原文本刊更多论文

Herpes simplex virus encephalitis: A literature review

HSVE (Herpes simplex virus encephalitis) is an infection caused by herpes simplex virus type 1 (HSV-1) or type 2 that produces neurologic problems. HSVE is associated with significant morbidity and mortality in adults even with antiviral medication, and it is a fatal disease in babies and children regardless of treatment. The most likely pathways include retrograde transmission through the olfactory or trigeminal nerves, as well as hematogenous spread. The most common presenting symptoms are encephalopathy, fever, convulsions, headache, and regional neurologic dysfunction. An accurate history and physical examination are required to identify Herpes simplex virus encephalitis (HSVE), and a prompt assessment is advised after the diagnosis has been established. HSVE is a neurodegenerative disease that may be fatal. Rapid diagnostic work-up and early diagnosis in all suspected or confirmed cases will result in early initiation of intravenous acyclovir, which may decrease morbidity and death.

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来源期刊

Romanian Journal of Neurology/ Revista Romana de Neurologie Medicine-Neurology (clinical)

CiteScore

0.40

自引率

0.00%

发文量

审稿时长

4 weeks

期刊介绍： ROMANIAN JOURNAL OF NEUROLOGY (Revista Română de Neurologie), the official journal of the Romanian Society of Neurology, was founded in 2001, being a prestigious scientific journal that provides a high quality in terms of scientific content, but also the editorial and graphic aspect, both through an impartial process of selection, evaluation and correction of articles (peer review procedure), as well as providing editorial, graphic and printing conditions at the highest level. In order to increase the scientific standards of the journal, special attention was paid to the improvement of the quality of the published materials. Guidance articles, clinical trials and case studies are structured in several sections: reviews, original articles, case reports, images in neurology. All articles are published entirely in English. A team of reputable medical professionals in the field of neurology is involved in a rigorous peer review process that complies with international ethics and quality rules in the academic world.