冠状动脉侧支生长的机制和潜在的治疗靶点

中华老年医学杂志 Pub Date : 2020-01-14 DOI:10.3760/CMA.J.ISSN.0254-9026.2020.01.019

Mengyang Zhang, J. Fan, Yacong Liu

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引用次数: 0

摘要

诱导冠状动脉侧支循环，即治疗性血管生成，被认为是治疗冠心病的一种有前景的方法。然而，冠状动脉侧支生长是一个复杂的过程，与多种因素有关。尽管它在动物实验中取得了有希望的结果，但临床试验迄今未能复制这些结果。在可行的临床治疗策略出现之前，还需要对冠状动脉侧支循环的生长机制进行进一步的研究。关键词：冠状动脉循环；抵押品流通

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Mechanisms and potential therapeutic targets for coronary collateral growth

Induction of coronary collateral circulation, that is, therapeutic angiogenesis, is considered a promising treatment for coronary heart disease.However, coronary collateral growth is a complex process and is related to a variety of factors.Although it has achieved promising outcomes in animal experiments, clinical trials have so far failed to replicate these results.Further studies on the growth mechanisms of coronary collateral circulation are still needed before a feasible clinical treatment strategy becomes available. Key words: Coronary circulation; Collateral circulatio

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中华老年医学杂志

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