开菲尔的抗菌、抗真菌和愈合性能研究

Nutrition Sante Pub Date : 2021-12-31 DOI:10.30952/ns.10.2.4
Nezha Sekkal-Taleb, Fatima Senouci, Ghazelane Medjahdi
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引用次数: 0

摘要

介绍。开非尔是由开非尔颗粒制备的微生物共生组合。目标。评价开非尔的抗菌、抗真菌和愈合活性。材料和方法。采用琼脂盘扩散法和well对金黄色葡萄球菌、铜绿假单胞菌、大肠杆菌、伤寒沙门氏菌、粪肠杆菌球菌、肺炎克雷伯菌、白色念珠菌等病原菌进行抑菌和抑菌试验。愈合实验在皮肤烧伤的成年Wistar大鼠中进行,使用局部应用两种牛奶,水果开菲尔凝胶和磺胺嘧啶银。结果。Kefiran是开菲尔菌的胞外多糖,具有抗菌、抗葡萄球菌和抗念珠菌活性。经过15天的治疗,与磺胺嘧啶银相比,开非尔凝胶具有更好的伤口愈合,对皮肤和结缔组织具有保护作用。结论。开菲尔是一种具有多种优点的天然益生菌。事实上,Kefiran具有抗葡萄球菌活性和抗念珠菌活性。与传统的磺胺嘧啶银治疗相比,开菲尔凝胶的愈合活性是一种有效的治疗方法,可以改善严重烧伤后的愈合。
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Study of antimicrobial, antifungal and healing properties of Kefir
Introduction. Kefir is a symbiotic association of microorganisms prepared from Kefir grains. Objective. The antibacterial, antifungal, and healing activity of Kefir was evaluated. Material and methods. Antibacterial and antifungal properties was carried out against some pathogenic microbial species, such as Staphylococcus aureus, Pseudomonas aeruginosa, Eschirichia-coli, Salmonella typhi, enterobacterococcus faecalis, Klebsiella pneumoniae, and Candida albicans, by the agar disk diffusion method and by well. Healing experiments were carried out in adult Wistar rats, with skin burns, using a topical application of two milk, and fruit kefir gels, and silver sulfadiazine. Results. Kefiran, an exopolysaccharide of Kefir, had antibacterial anti Staphylococcus activity and anti-candidal antifungal activity. Kefir gels had better wound healing compared to silver Sulfadiazine, with a protective effect on skin, and connective tissue, after a 15-day treatment ofrats. Conclusion. Kefir is a natural probiotic with multiple virtues. Indeed, Kefiran has an anti staphylococcus activity, and an anti candidias activity. Healing activity of Kefir gel is an effective therapeutic approach to improve healing, after a severe burn, compared to a conventional treatment with silver Sulfadiazine.
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