肥胖生存悖论与黑色素瘤相关死亡率

IF 0.5 4区社会学 Q3 AREA STUDIES

Israel Affairs Pub Date : 2023-08-18 DOI:10.1080/13537121.2023.2247668

Yuval Arbel, Y. Arbel, A. Kerner, M. Kerner

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引用次数: 0

摘要

黑色素瘤是一种越来越常见的皮肤癌，全球每年约有20万新发病例。本文旨在估计黑色素瘤死亡率、肥胖患病率和每10万人中每年新发黑色素瘤病例之间的关系。通过这样做，它使用二次模型来检验肥胖生存悖论的可能性，即反直觉的可能性，即较高的肥胖患病率降低了黑色素瘤的死亡风险。结果支持非单调关系，对肥胖与正常体重(BMI < 25)黑色素瘤患者的治疗决策具有影响。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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The obesity survival paradox and melanoma-related mortality

ABSTRACT Melanoma is an increasingly common skin cancer with approximately 200,000 new cases discovered annually worldwide. This article seeks to estimate the relationships between mortality rate from melanoma, prevalence of obesity and annual new melanoma cases per 100,000 persons in the population. By way of doing so, it uses a quadratic model to examine the possibility of the obesity survival paradox, namely, the counter-intuitive possibility that a higher prevalence of obesity reduces the mortality risk from melanoma. The outcomes support a non-monotonic relationship, with implications for treatment decisions regarding melanoma patients who are obese versus those with a normal weight (BMI < 25).

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来源期刊

Israel Affairs AREA STUDIES-

CiteScore

0.70

自引率

25.00%

发文量

期刊介绍： Whether your major interest is Israeli history or politics, literature or art, strategic affairs or economics, the Arab-Israeli conflict or Israel-diaspora relations, you will find articles and reviews that are incisive and contain even-handed analysis of the country and its problems in every issue of Israel Affairs, an international multidisciplinary journal. Scholarly and authoritative, yet straightforward and accessible, Israel Affairs aims to serve as a means of communication between the various communities interested in Israel: academics, policy-makers, practitioners, journalists and the informed public.