走向整体医学和整体生物学:继精准医学和系统生物学之后的生命科学

Q1 Biochemistry, Genetics and Molecular Biology

Frontiers in Life Science Pub Date : 2019-01-01 DOI:10.1080/21553769.2019.1682064

B. Yuan

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引用次数: 4

摘要

在生命科学领域，由于生物体的复杂性和适应性，系统生物学遇到了不可逾越的障碍。在不久的将来，精准医学有望建立个性化的状态描述体系和相应的靶向治疗体系，但疾病的综合治疗仍将是一个需要解决的重大难题。随着复杂性科学整体建模方法的成熟及其与中医方法的一致性日益显现，将整体建模方法引入生命科学将成为科学发展的必然。这种方法在生物学和医学领域的结合将导致“整体生物学”和“整体医学”的出现。整体医学是一种融合中医整体理念和以辨证为基础的治疗方法的个性化医疗体系。整体医学从根本上解决了复杂的生命系统整合问题，将适应性从理解生物体的障碍转变为更有效地调节和控制生物体不可或缺的工具。因此，继系统生物学和精准医学之后，将迎来整体医学和整体生物学的时代。

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Toward holistic medicine and holistic biology: life sciences after precision medicine and systems biology

In the field of life sciences, systems biology has encountered insurmountable obstacles caused by the complexity and adaptability of organisms. In the near future, precision medicine is expected to establish a personalized state-description system and a corresponding targeted-treatment system, but the comprehensive treatment of disease will remain a significant and difficult problem that needs to be resolved. As the holistic modeling method in complexity science matures and its concordance with traditional Chinese medicine (TCM) methods is increasingly revealed, the introduction of this method into the life sciences will become a necessity for scientific development. The incorporation of this method in the fields of biology and medicine will lead to the emergence of ‘holistic biology’ and ‘holistic medicine’. Holistic medicine is a personalized medicine system that incorporates TCM’s holistic concept and treatment approaches based on syndrome differentiation. Holistic medicine fundamentally solves the problem of complex life system integration and transforms adaptability from an obstacle for understanding organisms into an indispensable tool for more effective regulation and control of organisms. As a result, systems biology and precision medicine will be followed by an era of holistic medicine and holistic biology.

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来源期刊

Frontiers in Life Science MULTIDISCIPLINARY SCIENCES-

CiteScore

5.50

自引率

0.00%

发文量

期刊介绍： Frontiers in Life Science publishes high quality and innovative research at the frontier of biology with an emphasis on interdisciplinary research. We particularly encourage manuscripts that lie at the interface of the life sciences and either the more quantitative sciences (including chemistry, physics, mathematics, and informatics) or the social sciences (philosophy, anthropology, sociology and epistemology). We believe that these various disciplines can all contribute to biological research and provide original insights to the most recurrent questions.