柯萨奇病毒A6致手足口病的临床表现及治疗

中国小儿急救医学 Pub Date : 2019-11-20 DOI:10.3760/CMA.J.ISSN.1673-4912.2019.11.010

L. Liang, J. Qiu, Zhenghui Xiao

{"title":"柯萨奇病毒A6致手足口病的临床表现及治疗","authors":"L. Liang, J. Qiu, Zhenghui Xiao","doi":"10.3760/CMA.J.ISSN.1673-4912.2019.11.010","DOIUrl":null,"url":null,"abstract":"Hand-foot-and-mouth disease (HFMD) is a common infectious disease caused by human enterovirus (EVs). It is more common in children under 5 years of age.The clinical symptoms are mainly rash and herpes in the hands, feet, mouth and other parts.Some serious cases may suffer from serious complications in nervous system, respiratory system or circulatory system.Since 1998, HFMD has been mainly caused by enterovirus 71 and coxsackievirus A16 (CV-A16). In the past 10 years, coxsackievirus A6(CV-A6) has gradually replaced EV-71 and CV-A16, and become a main pathogen of HFMD.Many literatures have shown that CV-A6 often causes atypical HFMD, which is mainly characterized by a wider and more serious rash and desquamation, and even onychomadesis.At present, there are some reports on the prevalence and detection methods of HFMD caused by CV-A6.The paper reviewed on CV-A6 related etiology, epidemiology, clinical manifestations and treatment of HFMD. \n \n \nKey words: \nHand, foot and mouth disease; Coxsackie A6; Pathogen; Epidemiology; Clinical manifestations; Treatment","PeriodicalId":68901,"journal":{"name":"中国小儿急救医学","volume":"26 1","pages":"852-857"},"PeriodicalIF":0.0000,"publicationDate":"2019-11-20","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"The clinical manifestations and treatment of hand, foot and mouth disease caused by Coxsackievirus A6\",\"authors\":\"L. Liang, J. Qiu, Zhenghui Xiao\",\"doi\":\"10.3760/CMA.J.ISSN.1673-4912.2019.11.010\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Hand-foot-and-mouth disease (HFMD) is a common infectious disease caused by human enterovirus (EVs). It is more common in children under 5 years of age.The clinical symptoms are mainly rash and herpes in the hands, feet, mouth and other parts.Some serious cases may suffer from serious complications in nervous system, respiratory system or circulatory system.Since 1998, HFMD has been mainly caused by enterovirus 71 and coxsackievirus A16 (CV-A16). In the past 10 years, coxsackievirus A6(CV-A6) has gradually replaced EV-71 and CV-A16, and become a main pathogen of HFMD.Many literatures have shown that CV-A6 often causes atypical HFMD, which is mainly characterized by a wider and more serious rash and desquamation, and even onychomadesis.At present, there are some reports on the prevalence and detection methods of HFMD caused by CV-A6.The paper reviewed on CV-A6 related etiology, epidemiology, clinical manifestations and treatment of HFMD. \\n \\n \\nKey words: \\nHand, foot and mouth disease; Coxsackie A6; Pathogen; Epidemiology; Clinical manifestations; Treatment\",\"PeriodicalId\":68901,\"journal\":{\"name\":\"中国小儿急救医学\",\"volume\":\"26 1\",\"pages\":\"852-857\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-11-20\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"中国小儿急救医学\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.3760/CMA.J.ISSN.1673-4912.2019.11.010\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"中国小儿急救医学","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.3760/CMA.J.ISSN.1673-4912.2019.11.010","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}

引用次数: 1

摘要

手足口病是由人类肠道病毒引起的一种常见传染病。它在5岁以下的儿童中更为常见。临床症状主要是手、脚、口腔等部位的皮疹和疱疹。一些严重的病例可能会出现神经系统、呼吸系统或循环系统的严重并发症。自1998年以来，手足口病主要由肠道病毒71和柯萨奇病毒A16（CV-A16）引起。在过去的10年里，柯萨奇病毒A6（CV-A6）已逐渐取代EV-71和CV-A16，成为手足口病的主要病原体。许多文献表明，CV-A6常导致非典型手足口病，其主要特征是更广泛、更严重的皮疹和脱屑，甚至是甲癣。目前，关于由CV-A6引起的手足口病的发病率和检测方法已有一些报道。本文就CV-A6的病因、流行病学、临床表现和治疗等方面进行综述。关键词：手足口病；柯萨奇A6；病原体；流行病学；临床表现；治疗

本文章由计算机程序翻译，如有差异，请以英文原文为准。

查看原文本刊更多论文

The clinical manifestations and treatment of hand, foot and mouth disease caused by Coxsackievirus A6

Hand-foot-and-mouth disease (HFMD) is a common infectious disease caused by human enterovirus (EVs). It is more common in children under 5 years of age.The clinical symptoms are mainly rash and herpes in the hands, feet, mouth and other parts.Some serious cases may suffer from serious complications in nervous system, respiratory system or circulatory system.Since 1998, HFMD has been mainly caused by enterovirus 71 and coxsackievirus A16 (CV-A16). In the past 10 years, coxsackievirus A6(CV-A6) has gradually replaced EV-71 and CV-A16, and become a main pathogen of HFMD.Many literatures have shown that CV-A6 often causes atypical HFMD, which is mainly characterized by a wider and more serious rash and desquamation, and even onychomadesis.At present, there are some reports on the prevalence and detection methods of HFMD caused by CV-A6.The paper reviewed on CV-A6 related etiology, epidemiology, clinical manifestations and treatment of HFMD. Key words: Hand, foot and mouth disease; Coxsackie A6; Pathogen; Epidemiology; Clinical manifestations; Treatment

求助全文

通过发布文献求助，成功后即可免费获取论文全文。去求助

来源期刊

中国小儿急救医学

自引率

0.00%

发文量

6226

期刊介绍： Chinese Journal of Neurology was established in 1955, the predecessor of which is Chinese Journal of Neurology and Psychiatry. Chinese Journal of Neurology and Psychiatry has been indexed by MEDLINE until 1996, when it was divided into two journals, Chinese Journal of Neurology, and Chinese Journal of Psychiatry. Chinese Journal of Neurology is now indexed by EM, SCOPUS, AJ, WPRIM, CNKI, Wanfang Data, CSCD, etc. The impact factor of the journal is 2.755 in 2017, ranking the first among all neurological and psychological journals in China and among all the 142 medical journals published by the Chinese Medical Association. The journal is available both in print and online.