微波辅助Soxhlet技术提取辣木乙醇提取物中的生物活性物质

IF 0.3 Q4 PHARMACOLOGY & PHARMACY

Current Drug Therapy Pub Date : 2023-05-22 DOI:10.2174/1574885518666230522122556

Amerendra Singh, Santoshkumar Singh, P. Upadhyay, J. Mishra, V. Vishwakarma

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引用次数: 0

摘要

采用索氏提取和微波辅助提取技术在乙醇中提取辣木（Nimmo leaf），获得具有生物活性的化合物。采用标准技术对乙醇提取物进行了植物化学分析。分析证实了类黄酮、酚类、类固醇、生物碱、萜类、糖苷、单宁和皂苷的存在，也不存在蒽醌。此外，使用DPPH和ABTS测定法评估提取物的抗氧化活性。还测定了提取物的IC50值。叶提取物的总酚含量、总黄酮含量和抗氧化活性之间存在明显的相关性。结论：采用微波辅助提取技术，可以从辣木中提取出大量的酚类化合物，这可能是其抗氧化活性的原因。

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Characterization and Extraction of Bioactive Compounds in Ethanolic Extract of Moringa concanensis, Nimmo Leaf, Using Microwave-assisted and Soxhlet Techniques

The extraction of Moringa concanensis (Nimmo leaf) was done in ethanol using Soxhlet and microwave-assisted extraction (MAE) techniques to obtain bioactive compounds. The standard techniques were used to carry out phytochemical analysis of ethanolic extract. The analysis confirmed the presence of flavonoids, phenols, steroids, alkaloids, terpenoids, glycosides, tannins, and saponins, and also the absence of anthraquinones. Moreover, the extract was evaluated for antioxidant activities using DPPH and ABTS assays. The IC50 value of the extract was also determined. A clear correlation between the total phenolic content, total flavonoid content, and antioxidant activity of the leaf extracts was obtained. Conclusion: This study suggests that a high amount of phenolic compounds could be obtained from Moringa concanensis (Nimmo leaf) by using the microwave-assisted extraction technique, which may be responsible for its antioxidant activity.

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来源期刊

Current Drug Therapy PHARMACOLOGY & PHARMACY-

CiteScore

1.30

自引率

0.00%

发文量

期刊介绍： Current Drug Therapy publishes frontier reviews of high quality on all the latest advances in drug therapy covering: new and existing drugs, therapies and medical devices. The journal is essential reading for all researchers and clinicians involved in drug therapy.