髓外浆细胞瘤：一种罕见的实体瘤

IF 0.4 Q4 GASTROENTEROLOGY & HEPATOLOGY

Journal of Digestive Endoscopy Pub Date : 2023-03-01 DOI:10.1055/s-0042-1759511

Pastor Joaquín Ortiz Mendieta, L. Tolentino, D. Centeno, John Alexander Lata Guacho, L. Felipe, F. Maluf-Filho

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引用次数: 0

摘要

髓外浆细胞瘤是一种成熟B细胞通过克隆扩增产生免疫球蛋白的免疫增生性疾病。浆细胞肿瘤占所有胰腺肿块的不到0.1%，它们可以是原发性或继发于多发性骨髓瘤(MM)。我们提出的情况下，56岁的男子髓外孤立浆细胞瘤位于胰腺，表现为腹痛和黄疸。影像学特征与其他胰腺疾病相似，由于单克隆浆细胞均匀浸润，通常表达CD38和cd138标记物，并且存在kappa/lambda轻链，因此免疫组织化学证实了诊断。

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Extramedullary Plasmacytoma: A Rare Entity

Abstract Extramedullary plasmacytoma is an immunoproliferative disease of mature B cell that produces immunoglobulins by clonal expansion. Plasma cell neoplasms are responsible for less than 0.1% of all pancreatic masses, they can be primary or secondary to multiple myeloma (MM). We present the case of a 56-year-old man with extramedullary solitary plasmacytoma located in the pancreas, presented with abdominal pain and jaundice. Imaging characteristics are similar to those of other pancreatic diseases, and the diagnosis is confirmed by immunohistochemistry due to the presence of a homogeneous infiltrate of monoclonal plasma cells, which typically express CD38 and CD 138 markers and the presence of kappa/lambda light chains.

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来源期刊

Journal of Digestive Endoscopy GASTROENTEROLOGY & HEPATOLOGY-

自引率

28.60%

发文量

审稿时长

22 weeks

期刊介绍： The Journal of Digestive Endoscopy (JDE) is the official publication of the Society of Gastrointestinal Endoscopy of India that has over 1500 members. The society comprises of several key clinicians in this field from different parts of the country and has key international speakers in its advisory board. JDE is a double-blinded peer-reviewed, print and online journal publishing quarterly. It focuses on original investigations, reviews, case reports and clinical images as well as key investigations including but not limited to cholangiopancreatography, fluoroscopy, capsule endoscopy etc.