131mXe热升华发生器

Q3 Physics and Astronomy

Instruments Pub Date : 2022-11-16 DOI:10.3390/instruments6040076

K. Kulesz, N. Azaryan, M. Baranowski, Mateusz Jerzy Chojnacki, Ulli Köster, R. Lica, S. Pascu, R. Jolivet, M. Kowalska

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引用次数: 0

摘要

重惰性气体氙的稳定和不稳定同位素在各种医疗应用中都有应用。然而，除了用于单光子发射计算机断层扫描的133Xe外，氙的放射性同位素目前很难少量获得。考虑到GAMMA-MRI项目，我们研究了长寿命激发态（异构体）131mXe的热升华发生器。这种生产方法利用了从医院供应商以Na131I粉末形式商业获得的131I的衰变。Na131I粉末的热处理和释放的131mXe的低温捕获使我们能够收集高达88%的产生的氙。我们的方法提供了131mXe和131Xe的异构体混合物。随着可扩展性和化学纯化的改进，这种方法可能成为小规模实验中131mXe的成本效益高的来源。

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A Thermal Sublimation Generator of 131mXe

Stable and unstable isotopes of the heavy noble gas xenon find use in various medical applications. However, apart from 133Xe, used for Single Photon Emission Computed Tomography, radioactive isotopes of xenon are currently complicated to obtain in small quantities. With the GAMMA-MRI project in mind, we investigated a thermal sublimation generator of the long-lived excited state (isomer) 131mXe. This production method utilized the decay of 131I, obtained commercially from a hospital supplier in the form of Na131I powder. Heat treatments of the Na131I powder and cryogenic trapping of released 131mXe allowed us to collect up to 88% of the produced xenon. Our method provides an isomeric mixture of 131mXe and 131Xe. With improvements in scalability and chemical purification, this method could be a cost-effective source of 131mXe for small-scale experiments.

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来源期刊

Instruments Physics and Astronomy-Instrumentation

CiteScore

2.60

自引率

0.00%

发文量

审稿时长

11 weeks