当归四逆加五柱瘀生姜汤对正常人红细胞变形能力的影响:交叉试验

IF 2 4区医学 Q2 INTEGRATIVE & COMPLEMENTARY MEDICINE

Journal of Traditional Chinese Medicine Pub Date : 2018-10-01 DOI:10.1016/S0254-6272(18)30917-8

JiEun Lee , Seung-Yeon Cho , Seong-Uk Park , Woo-Sang Jung , Sang-Kwan Moon , Jung-Mi Park , Chang-Nam Ko , Ki-Ho Cho , Seungwon Kwon

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引用次数: 0

摘要

目的观察当归四逆联合五柱瘀生姜汤对正常人红细胞变形能力的影响。方法共纳入25例受试者，平均年龄(27.8±1.8)岁。该研究被设计为交叉试验，受试者参加2天。第一天，在基线和给水后1-2小时采集血液样本，而第二天，在基线血液采样后，受试者被给予DSWST而不是水。在基线和给水或DSWST后采集血液样本，检查红细胞变形能力。结果与摄入DSWST后的基线相比，延长指数在2 h后显著增加(P = 0.009)。然而，在饮水后，没有观察到显著差异。在比较DSWST与水对红细胞变形能力的百分比变化时，我们发现，在给药2 h后，与水相比，DSWST显著改善了红细胞变形能力(P <0.001)。结论dswst对正常人红细胞变形能力有短暂性影响。

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Effect of the herbal medicine Danggui Sini plus Wuzhuyu Shengjiang Tang on erythrocyte deformability in normal subjects: a cross-over trial

OBJECTIVE

To show whether Danggui Sini plus Wuzhuyu Shengjiang Tang (DSWST) has any transient effect on erythrocyte deformability in normal subjects.

METHODS

A total of 25 subjects [mean age (27.8 ± 1.8) years] was enrolled in this study. The study was designed as a cross-over trial in which the subjects took part for 2 d. On the first day, blood samples were collected at baseline and 1-2 h after administration of water, whereas, on the second day, instead of water, the subjects were administered DSWST after the baseline blood sampling. The blood samples collected at baseline and after the administration water or DSWST, were examined for erythrocyte deformability.

RESULTS

The elongation index increased significantly after 2 h (P = 0.009) compared to the baseline after DSWST intake. However, after water intake, there was no significant difference observed. When comparing the percent change of erythrocyte deformability between DSWST and water, we found that after 2 h of administration, DSWST improved erythrocyte deformability significantly compared to water (P < 0.001).

CONCLUSION

DSWST has a transient effect on erythrocyte deformability in normal subjects.

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来源期刊

Journal of Traditional Chinese Medicine INTEGRATIVE & COMPLEMENTARY MEDICINE-

CiteScore

2.40

自引率

3.80%

发文量

32269

审稿时长

2 months

期刊介绍： Journal of Traditional Chinese Medicine（JTCM） is devoted to clinical and theortical research on the use of acupuncture and Oriental medicine. The main columns include Clinical Observations, Basic Investigations, Reviews, Questions and Answers, an Expert''s Forum, and Discussions of Clinical Cases. Its key topics include acupuncture and electro-acupuncture, herbal medicine, homeopathy, masseotherapy, mind-body therapies, palliative care, and other CAM therapies.