R. C. Founou, J. Nwobegahay, R. Gandji, Cedrice Tsayem, Sandra Yopa, M. Kuété, Luria Leslie Founou
{"title":"喀麦隆一例非洲黑人慢性淋巴细胞白血病病例报告","authors":"R. C. Founou, J. Nwobegahay, R. Gandji, Cedrice Tsayem, Sandra Yopa, M. Kuété, Luria Leslie Founou","doi":"10.35248/2329-6917.19.7.254","DOIUrl":null,"url":null,"abstract":"Chronic lymphocytic leukemia (CLL) is an acquired monoclonal disorder characterized by a gradual accumulation of functionally incompetent lymphocytes. It generally presents a clonal B cells arrested in the B-cell differentiation pathway that resemble morphologically to mature lymphocytes in the peripheral blood. There is a scarcity of CLL data among sub-Saharan African countries such as Cameroon. We herein report a case of CLL that remained stable over a period of seven years in a 54 years old Black African man. The patient had no history of exposure to toxic chemicals or ionizing radiation and presented with several complaints and clinical symptoms. Clinical and laboratory investigations indicated a CLL in stage B of the Binet staging system. The dosage of chloraminophene led to a favourable outcome in the patient with the reduction of lymphocyte count, size of lymph nodes while relieving pain and improving general status and bone-marrow function of the patient.","PeriodicalId":90223,"journal":{"name":"Journal of leukemia (Los Angeles, Calif.)","volume":" ","pages":""},"PeriodicalIF":0.0000,"publicationDate":"2019-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Chronic Lymphocytic Leukemia in a Black African Man: A Cameroonian Case Report\",\"authors\":\"R. C. Founou, J. Nwobegahay, R. Gandji, Cedrice Tsayem, Sandra Yopa, M. Kuété, Luria Leslie Founou\",\"doi\":\"10.35248/2329-6917.19.7.254\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"Chronic lymphocytic leukemia (CLL) is an acquired monoclonal disorder characterized by a gradual accumulation of functionally incompetent lymphocytes. It generally presents a clonal B cells arrested in the B-cell differentiation pathway that resemble morphologically to mature lymphocytes in the peripheral blood. There is a scarcity of CLL data among sub-Saharan African countries such as Cameroon. We herein report a case of CLL that remained stable over a period of seven years in a 54 years old Black African man. The patient had no history of exposure to toxic chemicals or ionizing radiation and presented with several complaints and clinical symptoms. Clinical and laboratory investigations indicated a CLL in stage B of the Binet staging system. The dosage of chloraminophene led to a favourable outcome in the patient with the reduction of lymphocyte count, size of lymph nodes while relieving pain and improving general status and bone-marrow function of the patient.\",\"PeriodicalId\":90223,\"journal\":{\"name\":\"Journal of leukemia (Los Angeles, Calif.)\",\"volume\":\" \",\"pages\":\"\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2019-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of leukemia (Los Angeles, Calif.)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.35248/2329-6917.19.7.254\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of leukemia (Los Angeles, Calif.)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.35248/2329-6917.19.7.254","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Chronic Lymphocytic Leukemia in a Black African Man: A Cameroonian Case Report
Chronic lymphocytic leukemia (CLL) is an acquired monoclonal disorder characterized by a gradual accumulation of functionally incompetent lymphocytes. It generally presents a clonal B cells arrested in the B-cell differentiation pathway that resemble morphologically to mature lymphocytes in the peripheral blood. There is a scarcity of CLL data among sub-Saharan African countries such as Cameroon. We herein report a case of CLL that remained stable over a period of seven years in a 54 years old Black African man. The patient had no history of exposure to toxic chemicals or ionizing radiation and presented with several complaints and clinical symptoms. Clinical and laboratory investigations indicated a CLL in stage B of the Binet staging system. The dosage of chloraminophene led to a favourable outcome in the patient with the reduction of lymphocyte count, size of lymph nodes while relieving pain and improving general status and bone-marrow function of the patient.