碳皮激光治疗有色皮肤寻常性痤疮疗效的单中心前瞻性研究

Q3 Medicine
Anuj Bhatnagar, Debdeep Mitra, Karthi Kishore, Manish Kumar, Therasal Valarmathi, Arun Kumar, Rahul Kumar
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引用次数: 0

摘要

背景:寻常痤疮是一种慢性皮脂腺疾病,约 80% 的成年人都会患上。尽管有各种治疗方法的报道,但要治疗痤疮并将副作用降到最低却很困难。最近,外用碳悬浮剂结合 QsNdYAG 激光治疗(碳剥离激光技术)在有效治疗寻常型痤疮方面越来越受欢迎:研究碳换肤激光技术在治疗有色人种寻常痤疮(II-IV 级)中的疗效:前瞻性观察研究的对象是 35 名 II-IV 级寻常型痤疮患者,由于副作用或治疗失败,这些患者对局部/系统药物治疗的依从性较差,无法满足患者的期望。患者首先接受碳悬浮剂(Cosderma 碳凝胶)的局部治疗,然后使用两种模式(准长脉冲模式和 Q 开关模式 1064 纳米)的质量开关钕钇铝石榴石(Qs:NdYAG)激光进行治疗。治疗包括三次治疗,每次间隔两周。要求患者在此期间避免使用任何治疗痤疮的外用/系统药物:结果:经过三次 "碳剥离激光技术 "治疗后,红斑和结节性痤疮皮损明显减少。在 35 名患者中,28 人(80%)的皮损改善程度大于 80%,7 人(20%)的皮损改善程度在 50%-80%之间,表现为皮损数量减少、面积缩小、炎症程度减轻,没有患者对治疗无反应。术后并发症极少;6 名患者(20%)出现红斑,1 名患者(3.3%)出现轻微疼痛,可以忍受,没有炎症后色素沉着。与术前平均 ISGA 值 3.657 相比,术后平均 ISGA 值为 1.342,P 值为 结论:碳剥离激光技术是治疗有色皮肤寻常痤疮的有效方法,副作用小,效果显著。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Efficacy of Carbon Peel Laser in Acne Vulgaris in Skin of Color: A Single Center Prospective Study.

Background: Acne vulgaris is a chronic disease of pilosebaceous units that affects approximately 80% of adult population. Despite various treatment modalities being reported, treating acne with minimal side effects is difficult. Specifically, topical carbon suspension combined with QsNdYAG laser treatment (carbon peel laser technique) has gained popularity recently for effective treatment of acne vulgaris.

Objectives: To study the efficacy of carbon peel laser technique in the management of acne vulgaris (Grade II-IV) in skin of color.

Materials and methods: A prospective observational study was done on 35 patients who presented with acne vulgaris Grade II-IV, who were poorly compliant to treatment with topical/systemic agents owing to side effects or failure of treatment, to meet patient's expectations. The patients were subjected to an initial topical application of carbon suspension (Cosderma Carbon gel) followed by treatment with quality switching neodymium yttrium aluminum garnet (Qs:NdYAG) laser in two modes (quasi long pulsed mode followed by Q switched mode 1064 nm). The treatment consisted of three sittings with intervals of 2 weeks. The patients were asked to avoid use of any topical/systemic medication for acne during this period.

Results: Significant reduction of erythematous and nodular acne lesions was noted after three sittings of "carbon peel laser technique". Among 35 patients, 28 (80%) showed >80% improvement and 7 (20%) showed 50%-80% improvement in skin lesions in the form of decrease in the number and size of lesions and extent of inflammation, with no patients nonresponsive to treatment. The postprocedure complications were minimal; 6 (20%) developed erythema, and 1 (3.3%) patient developed mild tolerable pain with no post inflammatory hyper/hypopigmentation. The postprocedure mean ISGA (Investigator Status Global Assessment) was 1.342 as compared with preprocedure mean ISGA of 3.657 with value of P <0.0001.

Conclusion: Carbon peel laser technique is an effective method for the management of acne vulgaris in skin of color with minimal side effects and significant results.

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来源期刊
CiteScore
1.10
自引率
0.00%
发文量
60
审稿时长
29 weeks
期刊介绍: The journal will cover aspects of Dermatosurgery and Aesthetic surgery, including cutaneous surgical procedures, lasers, light based treatments and aesthetic treatments. Authors of articles addressing topics such as skin tumours, pigmentary disorders, histopathology, diagnostic techniques, drugs, applications of cosmeceuticals surgical aspects, including pre and post procedural care are highly encouraged to submit with us. The journal also publishes articles on topics in allied specialities suh as plastic surgery, maxillofacial surgery vascular surgery, oculoplastic surgery etc. that are relevant to Dermatosurgery. The journal gives preference to clinically oriented studies over experimental and animal studies. The Journal would publish peer-reviewed Original Research Articles, Systematic reviews, Narrative Reviews, Case reports, Innovations and Debates. Letters to the editor, practice points, pearls in cutaneous and aesthetic surgery, quiz page, images, novel techniques, newer uses of instruments and video presentations and ethical aspects of cutaneous and aesthetic surgery are also invited.
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