大疱性类天疱疮是一种罕见的自身免疫性疾病

S. Biradar, S. Dhanavidya, P. Kavya, T. Keerthi, N. Sunanda, S. Marapur, V. Warad, N. Kalyane
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引用次数: 1

摘要

背景。大疱性类天疱疮(BP)是一种罕见的自身免疫性皮肤病,主要表现为皮肤病变上的皮肤水泡。目的是强调罕见的BP病例。方法。一个病例报告BP在一个58岁的男性患者入院皮肤科病房提出。结果。58岁男性患者,主诉为充满液体的皮肤病变,最初在躯干检查,逐渐进展到上肢和下肢。尽管患者接受了皮质类固醇(地塞米松)和辅助药物的推荐治疗,但新的皮肤病变继续发展,患者的病情恶化。在治疗的第五天,以更高的剂量(50mg/天)开始使用泼尼松龙代替地塞米松,泼尼松龙证明了其对抗广泛性血压的有效性。结论。大疱性类天疱疮是一种令人痛苦的起泡皮肤病。由于易受感染和体液电解质紊乱,未经治疗的疾病往往是致命的。随着新疗法和治疗方式的出现,大疱性类天疱疮患者的死亡率已显著降低。与其他辅助药物一起,全身性和局部性皮质类固醇治疗是主要的治疗方法。在本病例研究中,泼尼松龙的应用证明了其在广泛的BP疾病状态下的有效性,并改善了患者的生活质量。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
BULLOUS PEMPHIGOID A RARE AUTOIMMUNE DISEASE: A CASE REPORT
Background. Bullous pemphigoid (BP) is a rare autoimmune blistering skin disease in the elderly and it is manifested by cutaneous blisters on the skin lesions. The objective was to emphasize the rare case of BP. Methods. A case report of BP in a 58-year-old male patient admitted to a dermatology ward is presented. Results. A 58-year-old male patient with complaints of fluid-filled skin lesions, was examined initially over the trunk, gradually progressed involving B/L upper and lower extremities. Even though the patient was treated with the recommended therapy of corticosteroid (Dexamethasone) along with adjuvant drugs, new skin lesions continued to develop, and the patient’s condition worsened. The Prednisolone was started in place of Dexamethasone on the fifth day of treatment at its higher dose (50mg/day), the Prednisolone proved its efficacy to combat the extensive condition of BP. Conclusions. Bullous pemphigoid is a distressing blistering skin disease. Untreated disease is often fatal because of the susceptibility to infection and fluid-electrolyte disturbances. The mortality of patients with bullous pemphigoid has been significantly reduced with the advent of new therapies and treatment modalities. The treatment with systemic and topical corticosteroids forms the mainstay of treatment along with other adjuvant drugs. In the present case study, the use of Prednisolone has proven its efficacy in the extensive disease state of BP and improved the patient’s quality of life.
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