腔内注射Marcaine和利多卡因治疗白内障术后疼痛和恢复的疗效和安全性比较

IF 0.4 Q4 NEUROSCIENCES

Archives of Neuroscience Pub Date : 2022-09-05 DOI:10.5812/ans-129165

Darioush Moradi Farsani, Nima Koosha, S. Yavari, A. Fotovat, H. Shetabi

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引用次数: 0

摘要

背景：白内障手术后，各种局部（房内）镇痛药用于缓解术后疼痛。目的：我们决定比较房内Marcaine和利多卡因对白内障手术后疼痛强度的影响。方法：在这项双盲、随机的临床试验中，64名白内障手术患者被随机分配为利多卡因或布比卡因（Marcaine）前房内注射麻醉。研究终点包括疼痛评分、血液动力学状态、患者满意度和恢复时间。结果：Marcaine组的恢复时间比另一组短（P=0.001）。接受Marcaine治疗的患者在术后不同时间点的平均疼痛评分显著低于接受利多卡因治疗的患者（P<0.001）。我们的研究表明，与利多卡因组相比，患者对Marcaine的满意度更高（P=0.026）。然而，两组术后血流动力学状态相似。结论：与利多卡因相比，房内注射Marcaine可缩短白内障手术后的术后恢复期，减轻疼痛强度，提高患者的满意度。

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Comparing Efficacy and Safety of Intracameral Injection of Marcaine and Lidocaine on Postoperative Pain and Recovery After Cataract Surgery

Background: Various topical (intracameral) analgesics are used to relieve postoperative pain after cataract surgery. Objectives: We decided to compare the effects of intracameral Marcaine and lidocaine on pain intensity after the cataract operation. Methods: In this double-blind, randomized clinical trial, 64 patients who were candidates for cataract surgery were randomly assigned to either anesthesia with lidocaine or bupivacaine (Marcaine) by intracameral injection. Study endpoints included pain score, hemodynamic status, patient satisfaction, and recovery duration. Results: The Marcaine group experienced a shorter recovery than another group (P = 0.001). The mean pain score at the different time points after the operation was significantly lower in the group receiving Marcaine than those receiving lidocaine (P < 0.001). Our study showed a higher level of patients’ satisfaction with Marcaine as compared to the lidocaine group (P = 0.026). However, postoperative hemodynamic status was similar in both groups. Conclusions: Compared with lidocaine, intracameral injection of Marcaine results in a shorter postoperative recovery period, reduced pain intensity, and higher satisfaction among patients after cataract surgery.

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来源期刊

Archives of Neuroscience NEUROSCIENCES-

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期刊介绍： Archives of neuroscience is a clinical and basic journal which is informative to all practitioners like Neurosurgeons, Neurologists, Psychiatrists, Neuroscientists. It is the official journal of Brain and Spinal Injury Research Center. The Major theme of this journal is to follow the path of scientific collaboration, spontaneity, and goodwill for the future, by providing up-to-date knowledge for the readers. The journal aims at covering different fields, as the name implies, ranging from research in basic and clinical sciences to core topics such as patient care, education, procuring and correct utilization of resources and bringing to limelight the cherished goals of the institute in providing a standard care for the physically disabled patients. This quarterly journal offers a venue for our researchers and scientists to vent their innovative and constructive research works. The scope of the journal is as far wide as the universe as being declared by the name of the journal, but our aim is to pursue our sacred goals in providing a panacea for the intractable ailments, which leave a psychological element in the daily life of such patients. This authoritative clinical and basic journal was founded by Professor Madjid Samii in 2012.