医用活性炭吸附色氨酸和苯丙氨酸的选择性研究

IF 0.7 4区化学 Q4 CHEMISTRY, MULTIDISCIPLINARY

Theoretical and Experimental Chemistry Pub Date : 2023-05-19 DOI:10.1007/s11237-023-09766-5

I. A. Farbun, V. A. Trykhlib

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引用次数: 1

摘要

碳吸附剂KARBON™对色氨酸和苯丙氨酸的吸附能力从单独的溶液，它们的混合物，并在亮氨酸，异亮氨酸和缬氨酸的存在进行了研究。可以确定的是，在从这些氨基酸的混合物中吸附时，色氨酸和苯丙氨酸的总体去除率超过脂肪族类似物的去除率一个数量级。色氨酸和苯丙氨酸的最大去除率在2.0 ~ 2.8 mmol/L时达到90%，当浓度增加到20 ~ 24 mmol/L时，这些氨基酸的去除率下降约2倍。所获得的数据表明，吸附剂KARBON™的肠道萃取剂可作为多种疾病的氨基酸治疗的替代品。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

Selectivity of Tryptophan and Phenylalanine Adsorption by Activated Coconut Carbon of Medical Assignment

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Selectivity of Tryptophan and Phenylalanine Adsorption by Activated Coconut Carbon of Medical Assignment

The adsorption capacity of carbon adsorbent KARBON™ for tryptophan and phenylalanine from the individual solutions, their mixtures, and in the presence of leucine, isoleucine, and valine has been studied. It is established that, at the adsorption from the mixture of these amino acids, the overall removal of tryptophan and phenylalanine is an order of magnitude exceeding the removal of aliphatic analogues. Maximum removals (>90%) of tryptophan and phenylalanine are achieved at concentrations of 2.0-2.8 mmol/L, as the concentrations increase to 20-24 mmol/L, the efficiency of the removal of these amino acids is decreased approximately twice. The obtained data show that the enterofraction of the adsorbent KARBON™ can be used as an alternative to amino acid therapy for various diseases.

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来源期刊

Theoretical and Experimental Chemistry CHEMISTRY, MULTIDISCIPLINARY-

CiteScore

1.60

自引率

10.00%

发文量

审稿时长

6-12 weeks

期刊介绍： Theoretical and Experimental Chemistry is a journal for the rapid publication of research communications and reviews on modern problems of physical chemistry such as: a) physicochemical bases, principles, and methods for creation of novel processes, compounds, and materials; b) physicochemical principles of chemical process control, influence of external physical forces on chemical reactions; c) physical nanochemistry, nanostructures and nanomaterials, functional nanomaterials, size-dependent properties of materials.