Xueliang Fu, JianYu Yang, De-Jun Liu, Y. Huo, Wei Liu, Jun-Feng Zhang, R. Hua, Yong-wei Sun
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Prognostic factors of survival for patients with duodenal papilla carcinoma after pancreaticoduodenectomy
Objective
To investigate the prognostic factors of survival for patients with duodenal papilla carcinoma (DPC) after pancreaticoduodenectomy.
Methods
98 DPC patients undergoing pancreaticoduodenectomy with follow-up from Jan 2010 to Dec 2017 at Renji Hospital, School of Medicine, Shanghai Jiao Tong University were analyzed retrospectively.
Results
80 Cases were followed up. The 1, 3, and 5 year survival rates of 80 patients were 89.9%, 72.4%, and 66.6%, respectively. Univariate analysis showed tumor size, T stage, N stage, TNM stage, tissue differentiation degree were related to postoperative survival(all P<0.05). Multivariate analysis showed that tumor size, N stage, TNM stage, and tissue differentiation degree were independent factors influencing postoperative prognosis(all P<0.05).
Conclusions
Tumor size, N stage, TNM stage and tumor tissue differentiation degree were independent factors influencing the prognosis of DPC after pancreaticoduodenectomy, suggesting that early diagnosis, early treatment and radical resection were the key to improve the postoperative prognosis of DPC.
Key words:
Duodenal neoplasms; Pancreaticoduodenectomy; Prognosis
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