EV Gantsgorn, OV Denisenko, YaO Osipenko, DA Kalmykova, AV Ivanov, S. Gerasyuta, G. Bulguryan, M. Ivanova, D. Saakyan
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Type 1 diabetes mellitus: features of differential diagnosis
Type 1 diabetes mellitus is a condition caused by autoimmune damage to insulin–producing beta cells of the pancreatic islets, leading to endogenous insulin deficiency. Despite the sufficient knowledge of the disease and the availability of clinical recommendations for substitution therapy, the number of patients with this pathology is growing worldwide. At the same time, their cohort is very heterogeneous, including amid different etiology, concomitant genetic background, variations in the manifestation of the disease and severity. In this regard, traditional ideas about type 1 diabetes mellitus are being questioned, which requires special attention when managing patients with a clinical picture of the disease that differs from the traditional one. The article presents a clinical case of type 1 diabetes mellitus in a young patient, which demonstrates the importance of a personalized approach to the diagnosis and treatment of diabetic patients with a "non-classical" history.
期刊介绍:
Bulletin of Russian State Medical University (Bulletin of RSMU, ISSN Print 2500–1094, ISSN Online 2542–1204) is a peer-reviewed medical journal of Pirogov Russian National Research Medical University (Moscow, Russia). The original language of the journal is Russian (Vestnik Rossiyskogo Gosudarstvennogo Meditsinskogo Universiteta, Vestnik RGMU, ISSN Print 2070–7320, ISSN Online 2070–7339). Founded in 1994, it is issued once every two months publishing articles on clinical medicine and medical and biological sciences, first of all oncology, neurobiology, allergy and immunology, medical genetics, medical microbiology and infectious diseases. Every issue is thematic. Deadlines for manuscript submission are announced in advance. The number of publications on topics in spite of the issue topic is limited. The journal accepts only original articles submitted by their authors, including articles that present methods and techniques, clinical cases and opinions. Authors must guarantee that their work has not been previously published elsewhere in whole or in part and in other languages and is not under consideration by another scientific journal. The journal publishes only one review per issue; the review is ordered by the editors.