G. Cordero González , C.G. Máynez González , M.O. Echaniz-Avilés , S. Carrera Muiños , E. Yllescas Medrano , E. Corral Kassian , L.A. Fernández Carrocera
{"title":"3家医院新生儿< 1500克的积极肠外营养和平均生长速度。墨西哥城的er级","authors":"G. Cordero González , C.G. Máynez González , M.O. Echaniz-Avilés , S. Carrera Muiños , E. Yllescas Medrano , E. Corral Kassian , L.A. Fernández Carrocera","doi":"10.1016/j.rprh.2018.04.007","DOIUrl":null,"url":null,"abstract":"<div><h3>Introduction</h3><p>«Aggressive» parenteral nutrition <strong>(</strong>PN) may improve birth-weight recovery (BWR) and early weight gain.</p></div><div><h3>Objective</h3><p>To compare BWR and mean growth rate (MGR) with 2<!--> <!-->nutrition strategies.</p></div><div><h3>Material and methods</h3><p>A comparative descriptive analysis was performed on 64 newborns with birth-weight<!--> <!--><<!--> <!-->1500<!--> <!-->g admitted to the Neonatal Intensive Care Unit of the National Institute of Perinatology (México City) in 2013 (A) vs. 34 neonates of 2001 with same birth-weight (B). The variables recorded were, weight loss during first week, recovery birth-weight, MGR for weight, length, and head circumference in the 1st, 2nd, and 3rd week, intake of proteins, lipids and glucose in PN within first 24<!--> <!-->h of life, and days using PN. Statistical analysis included the mean, SD, and Student <em>t</em> test, was performed using with SPSS v. 20.</p></div><div><h3>Results</h3><p>MGR in 1st week, A<!--> <!-->=<!--> <!-->2.5 vs. B<!--> <!-->=<!--> <!-->−20 (<em>P</em> <!-->=<!--> <!-->0.004), in the 2nd, 11.7 vs. −6.4 (<em>P</em> <!-->=<!--> <!-->0.000), and in the 3rd 12.2 vs. −5.6<!--> <!-->g/kg/d (<em>P</em> <!-->=<!--> <!-->0.000); length 0.076 vs. 0.039 (<em>P</em> <!-->=<!--> <!-->0.010), and head circumference 0.075 vs. 0.035<!--> <!-->cm/day (<em>P</em> <!-->=<!--> <!-->.018). Weight loss 16.6 vs. 24.41<!--> <!-->g/day (<em>P</em> <!-->=<!--> <!-->0.000). Mean birth-weight recovery 11.5 vs. 41.4 days (<em>P</em> <!-->=<!--> <!-->0.000). PN initiated: glucose of 6.1<!--> <!-->mg/kg per min vs. 6 (<em>P</em> <!-->=<!--> <!-->0.000), protein 3.05 vs. 1.46 (<em>P</em> <!-->=<!--> <!-->0.000), and lipids 1.77 vs. 1.01<!--> <!-->g/kg per day (<em>P</em> <!-->=<!--> <!-->0.001). Calorie intake by the first PN was 48.8 vs. 35.4<!--> <!-->kcal (<em>P</em> <!-->=<!--> <!-->0.000). In group A, the mean duration of PN was 21.2 d and initiation of enteral feeding at 5 day.</p></div><div><h3>Conclusion</h3><p>Aggressive PN from first day of life showed reduced nutritional deficiency and posnatal growth restriction.</p></div>","PeriodicalId":32275,"journal":{"name":"Perinatologia y Reproduccion Humana","volume":"32 2","pages":"Pages 54-59"},"PeriodicalIF":0.0000,"publicationDate":"2018-06-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.rprh.2018.04.007","citationCount":"1","resultStr":"{\"title\":\"Nutrición parenteral agresiva y velocidad media de crecimiento en recién nacidos <1,500 g en un hospital de 3.er nivel de la Ciudad de México\",\"authors\":\"G. Cordero González , C.G. Máynez González , M.O. Echaniz-Avilés , S. Carrera Muiños , E. Yllescas Medrano , E. Corral Kassian , L.A. Fernández Carrocera\",\"doi\":\"10.1016/j.rprh.2018.04.007\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><h3>Introduction</h3><p>«Aggressive» parenteral nutrition <strong>(</strong>PN) may improve birth-weight recovery (BWR) and early weight gain.</p></div><div><h3>Objective</h3><p>To compare BWR and mean growth rate (MGR) with 2<!--> <!-->nutrition strategies.</p></div><div><h3>Material and methods</h3><p>A comparative descriptive analysis was performed on 64 newborns with birth-weight<!--> <!--><<!--> <!-->1500<!--> <!-->g admitted to the Neonatal Intensive Care Unit of the National Institute of Perinatology (México City) in 2013 (A) vs. 34 neonates of 2001 with same birth-weight (B). The variables recorded were, weight loss during first week, recovery birth-weight, MGR for weight, length, and head circumference in the 1st, 2nd, and 3rd week, intake of proteins, lipids and glucose in PN within first 24<!--> <!-->h of life, and days using PN. Statistical analysis included the mean, SD, and Student <em>t</em> test, was performed using with SPSS v. 20.</p></div><div><h3>Results</h3><p>MGR in 1st week, A<!--> <!-->=<!--> <!-->2.5 vs. B<!--> <!-->=<!--> <!-->−20 (<em>P</em> <!-->=<!--> <!-->0.004), in the 2nd, 11.7 vs. −6.4 (<em>P</em> <!-->=<!--> <!-->0.000), and in the 3rd 12.2 vs. −5.6<!--> <!-->g/kg/d (<em>P</em> <!-->=<!--> <!-->0.000); length 0.076 vs. 0.039 (<em>P</em> <!-->=<!--> <!-->0.010), and head circumference 0.075 vs. 0.035<!--> <!-->cm/day (<em>P</em> <!-->=<!--> <!-->.018). Weight loss 16.6 vs. 24.41<!--> <!-->g/day (<em>P</em> <!-->=<!--> <!-->0.000). Mean birth-weight recovery 11.5 vs. 41.4 days (<em>P</em> <!-->=<!--> <!-->0.000). PN initiated: glucose of 6.1<!--> <!-->mg/kg per min vs. 6 (<em>P</em> <!-->=<!--> <!-->0.000), protein 3.05 vs. 1.46 (<em>P</em> <!-->=<!--> <!-->0.000), and lipids 1.77 vs. 1.01<!--> <!-->g/kg per day (<em>P</em> <!-->=<!--> <!-->0.001). 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引用次数: 1
摘要
“积极”肠外营养(PN)可能改善出生体重恢复(BWR)和早期体重增加。目的比较两种营养策略下的体重比和平均生长率(MGR)。资料与方法对64例新生儿的出生体重进行描述性比较分析。2013年，全国围产期研究所新生儿重症监护病房收治了1500克新生儿(A)，而2001年出生体重相同的新生儿有34名(B)。记录的变量包括:第一周体重减轻、出生体重恢复、第1、2和3周体重、身长和头围的MGR，出生后24小时内PN中蛋白质、脂质和葡萄糖的摄入量，以及使用PN的天数。统计学分析采用SPSS v. 20进行均数、标准差和学生t检验。结果第1周smgr A = 2.5 vs. B = - 20 (P = 0.004)，第2周smgr A = 11.7 vs. - 6.4 (P = 0.000)，第3周smgr A = 12.2 vs. - 5.6 g/kg/d (P = 0.000);长度0.076 vs. 0.039 (P = 0.010)，头围0.075 vs. 0.035 cm/天(P = 0.018)。体重减轻16.6比24.41 g/d (P = 0.000)。平均出生体重恢复11.5天对41.4天(P = 0.000)。PN启动:葡萄糖为6.1 mg/kg / min vs. 6 (P = 0.000)，蛋白质为3.05 vs. 1.46 (P = 0.000)，脂质为1.77 vs. 1.01 g/kg / min (P = 0.001)。第一个PN的卡路里摄入量为48.8比35.4 kcal (P = 0.000)。A组平均PN持续时间为21.2 d，第5天开始肠内喂养。结论侵袭性PN从出生第一天起就表现出营养缺乏和出生后生长限制的减少。
Nutrición parenteral agresiva y velocidad media de crecimiento en recién nacidos <1,500 g en un hospital de 3.er nivel de la Ciudad de México
Introduction
«Aggressive» parenteral nutrition (PN) may improve birth-weight recovery (BWR) and early weight gain.
Objective
To compare BWR and mean growth rate (MGR) with 2 nutrition strategies.
Material and methods
A comparative descriptive analysis was performed on 64 newborns with birth-weight < 1500 g admitted to the Neonatal Intensive Care Unit of the National Institute of Perinatology (México City) in 2013 (A) vs. 34 neonates of 2001 with same birth-weight (B). The variables recorded were, weight loss during first week, recovery birth-weight, MGR for weight, length, and head circumference in the 1st, 2nd, and 3rd week, intake of proteins, lipids and glucose in PN within first 24 h of life, and days using PN. Statistical analysis included the mean, SD, and Student t test, was performed using with SPSS v. 20.
Results
MGR in 1st week, A = 2.5 vs. B = −20 (P = 0.004), in the 2nd, 11.7 vs. −6.4 (P = 0.000), and in the 3rd 12.2 vs. −5.6 g/kg/d (P = 0.000); length 0.076 vs. 0.039 (P = 0.010), and head circumference 0.075 vs. 0.035 cm/day (P = .018). Weight loss 16.6 vs. 24.41 g/day (P = 0.000). Mean birth-weight recovery 11.5 vs. 41.4 days (P = 0.000). PN initiated: glucose of 6.1 mg/kg per min vs. 6 (P = 0.000), protein 3.05 vs. 1.46 (P = 0.000), and lipids 1.77 vs. 1.01 g/kg per day (P = 0.001). Calorie intake by the first PN was 48.8 vs. 35.4 kcal (P = 0.000). In group A, the mean duration of PN was 21.2 d and initiation of enteral feeding at 5 day.
Conclusion
Aggressive PN from first day of life showed reduced nutritional deficiency and posnatal growth restriction.
期刊介绍：
Perinatología y Reproducción Humana is the official journal of the Instituto Nacional de Perinatología, Mexico. It is aimed at physicians of the area of perinatal and reproductive health (obstetrics and gynecology, maternal and fetal medicine, pediatricians, neonatologists, endocrinologists, infectious disease specialists, and neurologists) and also at health sciences professionals involved in the study of reproduction perinatal and reproductive health (chemists, biologists and neuro-physiologists). It is an electronic biannual journal, that publishes peer-reviewed original articles, in-deep reviews, letters to the editor and special sections related to basic, epidemiological, surgical, and clinical aspects in the area of perinatal and reproductive health, in English or Spanish languages and open access.
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