手机射频电磁辐射对SD大鼠氧化应激和进食行为的影响

Q4 Pharmacology, Toxicology and Pharmaceutics
Pravallika Pagadala, Vinutha Shankar M S, Sumathi M E
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引用次数: 0

摘要

众所周知,来自手机的射频电磁辐射(RF-EMR)会产生应激反应,因为它会影响下丘脑。手机已经成为我们生活中不可或缺的一部分,使用量的增加不仅体现在用户数量上,还体现在通话时间的增加上。本研究旨在研究手机射频电磁辐射对Sprague-Dawley(SD)大鼠氧化应激和进食行为评估的影响。在研究开始前,将12只10–12周龄、体重180–220 g的雄性SD大鼠安置在一个具有12:12小时明暗循环的房间中,并允许其适应任意量的食物和反渗透(RO)水。然后,将大鼠分为对照组和RF-EMR暴露组,并测量每天的采食量和体重。在研究期结束时,通过眶后穿刺采集血样进行生化调查。本研究显示,暴露于RF-EMR的大鼠的丙二醛和血清皮质酮水平显著升高,并降低了喂食行为。本研究证明,移动RF-EMR会导致氧化应激和氧化损伤,从而降低SD大鼠的喂食行为。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Effect of mobile phone radiofrequency electromagnetic radiations on oxidative stress and feeding behaviour in Sprague Dawley (SD) rats
Radiofrequency electromagnetic radiation (RF-EMR) from mobile phones is known to produce a stress response because of its effect on hypothalamus. Mobile phones have become an integral part of our lives with increasing usage not only in terms of number of users but also increase in talk time. The present study aimed to study the effect of mobile phone radiofrequency electromagnetic radiations on oxidative stress and feeding behaviour assessment in Sprague Dawley (SD) rats. Twelve male SD rats of 10–12 weeks old, weighing 180–220 g, were housed and allowed to acclimatise in a room with 12:12 h light-dark cycle with ad libitum amount of food and reverse osmosis (RO) water before the start of the study. Then, rats were divided into control and RF-EMR exposed groups, and everyday feed intake and body weight were measured. At the end of the study period, blood sample was collected through retro orbital puncture for biochemical investigations. The present study showed significant increase in malondialdehyde and serum corticosterone levels and decrease feeding behaviour in rats exposed to RF-EMR in rats exposed to RF-EMR. This study proves that mobile RF-EMR causes oxidative stress and oxidative damage leading to decreased feeding behaviour in SD rats.
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来源期刊
Indian journal of physiology and pharmacology
Indian journal of physiology and pharmacology Pharmacology, Toxicology and Pharmaceutics-Pharmacology
CiteScore
0.50
自引率
0.00%
发文量
35
期刊介绍: Indian Journal of Physiology and Pharmacology (IJPP) welcomes original manuscripts based upon research in physiological, pharmacological and allied sciences from any part of the world.
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