lanatum的植物化学、抗氧化、抗炎和溶栓特性采用。Don

IF 2.3 Q2 BIOLOGY

Scientifica Pub Date : 2022-05-26 DOI:10.1155/2022/5660527

Minhajur Rahman, Abu Taleb Surag, Roxy Begum, Md. Shakhuat Hossain Tusher, M. K. Huda

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引用次数: 2

摘要

首次对lanatum(科:兰科)的植物化学、抗氧化、抗炎和溶栓特性进行了研究。所有研究的植物化学物质在定性筛选中都有不同程度的鉴定。在定量筛选中，最多检出106.02±0.08 mg/g生物碱(根)、179.67±8.83 mg/g酚类(茎)、17.34±0.88 mg/g黄酮类(茎)、73.67±1.76 mg/g单宁(茎)和180.04±0.02 mg/ mL蛋白质(根)。通过自由基清除实验、热诱导白蛋白变性实验和凝血抑制实验，研究了抗氧化、抗炎和溶栓特性。其中根提取物的抗氧化和抗炎作用最显著(IC50 = 67.98 μg/mL)，抗炎作用最显著(IC50 = 60.86 μg/mL)，而茎提取物的溶栓作用最显著(IC50 = 163.8 μg/mL)。所研究的生物活性也呈显著正相关(r = 0.9;P < 0.05)，与酚类和单宁含量呈正相关。

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Phytochemical, Antioxidant, Anti-Inflammatory, and Thrombolytic Properties of Cleisomeria lanatum (Lindl.) Lindl. ex G. Don

For the first time, Cleisomeria lanatum (family: Orchidaceae) has been investigated for its phytochemical, antioxidant, anti-inflammatory, and thrombolytic properties. All phytochemicals studied were identified in varying degrees during qualitative screening. In quantitative screening, a maximum of 106.02 ± 0.08 mg/g alkaloids (root), 179.67 ± 8.83 mg/g phenols (stem), 17.34 ± 0.88 mg/g flavonoids (stem), 73.67 ± 1.76 mg/g tannins (stem), and 180.04 ± 0.02 μg/mL proteins (root) were detected. Antioxidant, anti-inflammatory, and thrombolytic properties were investigated using a free-radical scavenging assay, heat-induced albumin denaturation assay, and blood clotting inhibition assay. The root extracts had the most effective antioxidant (IC50 = 67.98 μg/mL) and anti-inflammatory (IC50 = 60.86 μg/mL) properties, whereas the stem extracts had the most effective thrombolytic property (IC50 = 163.8 μg/mL). The bioactivities studied also had a significant positive relationship (r = 0.9; p < 0.05) with the amount of phenolics and tannins.

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来源期刊

Scientifica BIOLOGY-

CiteScore

6.70

自引率

0.00%

发文量

审稿时长

21 weeks

期刊介绍： Scientifica is a peer-reviewed, Open Access journal that publishes research articles, review articles, and clinical studies covering a wide range of subjects in the life sciences, environmental sciences, health sciences, and medicine. The journal is divided into the 65 subject areas.