甲状腺激素和性激素比值能预测乳腺癌风险吗?一项对斯里兰卡乳腺癌患者的初步研究

IF 0.3 Q4 HEALTH CARE SCIENCES & SERVICES

Journal of Basic and Clinical Health Sciences Pub Date : 2023-02-24 DOI:10.30621/jbachs.1078216

H. Akalanka, S. Ekanayake, K. Samarasi̇nghe

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摘要

目的:甲状腺相关疾病和性激素与乳腺癌(BC)的关系报道，但结果不确定。目的:本研究旨在分析BC患者的甲状腺/性激素比率。方法:分析30 ~ 75岁新诊断乳腺癌患者(n=155)和年龄匹配的正常对照(n=75)的TSH、T3、T4、雌激素、孕酮和睾酮浓度。甲状腺:性激素比值计算。收集甲状腺相关疾病病史资料。结果与讨论:甲状腺相关疾病史明显增高(p

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Are thyroid and sex hormone ratios predictive of breast cancer risk? a preliminary study among a cohort of Sri Lankan breast cancer patients

Purpose: The association of thyroid related diseases and sex hormones with breast cancer (BC) is reported with inconclusive results. Objectives: The study was designed to analyze the thyroid/sex hormone ratios of BC patients. Methodology: TSH, T3, T4, estrogen, progesterone and testosterone concentrations of newly diagnosed breast cancer patients (n=155) aged 30 to 75 years and age-matched normal controls (n=75) were analyzed. Thyroid: sex hormone ratios were calculated. Data on history of thyroid related diseases were collected. Results and Discussion: History of thyroid related diseases was significantly higher (p

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Journal of Basic and Clinical Health Sciences HEALTH CARE SCIENCES & SERVICES-

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