Rola Khedraki, Austin A Robinson, Timothy Jordan, Justin L Grodin, Rajeev C Mohan
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引用次数: 0
摘要
综述的目的:确定心脏淀粉样变性(CA)的早期有效诊断对于避免不良后果至关重要。我们回顾了目前可帮助早期诊断、提供预后信息并可能跟踪 CA 治疗反应的成像工具:目前有几种常规成像模式可帮助诊断 CA,包括心电图、超声心动图、骨闪烁扫描、心脏计算机断层扫描(CT)和心脏磁共振(CMR)成像。包括左心房和右心室应变、CMR T1 和 T2 映像以及 ECV 定量在内的先进成像技术可为诊断提供替代性无创手段、更精细的预后判断以及跟踪治疗反应的能力。需要不断进行研究,以帮助确定成像标记物,从而提高诊断、分型和管理这种疾病的能力。
A Review of Current and Evolving Imaging Techniques in Cardiac Amyloidosis.
Purpose of review: Establishing an early, efficient diagnosis for cardiac amyloid (CA) is critical to avoiding adverse outcomes. We review current imaging tools that can aid early diagnosis, offer prognostic information, and possibly track treatment response in CA.
Recent findings: There are several current conventional imaging modalities that aid in the diagnosis of CA including electrocardiography, echocardiography, bone scintigraphy, cardiac computed tomography (CT), and cardiac magnetic resonance (CMR) imaging. Advanced imaging techniques including left atrial and right ventricular strain, and CMR T1 and T2 mapping as well as ECV quantification may provide alternative non-invasive means for diagnosis, more granular prognostication, and the ability to track treatment response.
Summary: Leveraging a multimodal imaging toolbox is integral to the early diagnosis of CA; however, it is important to understand the unique role and limitations posed by each modality. Ongoing studies are needed to help identify imaging markers that will lead to an enhanced ability to diagnose, subtype and manage this condition.
期刊介绍:
This journal aims to review the most important, recently published treatment-related advances in cardiovascular medicine. By providing clear, insightful, balanced contributions by international experts, the journal intends to elucidate novel approaches to treatment in those affected by the spectrum of cardiovascular-related diseases and conditions. We accomplish this aim by appointing international authorities to serve as Section Editors in key subject areas, such as coronary artery disease, cerebrovascular disease and stroke, heart failure, pediatric and congenital heart disease, and valvular, myocardial, pericardial, and cardiopulmonary diseases. Section Editors, in turn, select topics for which leading experts contribute comprehensive review articles that emphasize new developments and recently published papers of major importance, highlighted by annotated reference lists. We also provide commentaries from well-known figures in the field, and an international Editorial Board reviews the annual table of contents, suggests articles of special interest to their country/region, and ensures that topics are current and include emerging research.