关于开始使用抗肿瘤坏死因子生物制剂治疗潜伏性结核感染的建议

Cecilia Kit Ying O’Young, K. Ho, Hoch So, T. Mok, C. Leung, C. Chau, C. Chan
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引用次数: 2

摘要

使用抗肿瘤坏死因子(TNF)药物的免疫介导炎症性疾病患者发展为活动性结核病(TB)的风险增加。使用标准筛查方案筛查和治疗潜伏性结核病感染(LTBI)对于降低抗TNF药物治疗期间结核病再激活的风险非常重要。卫生部和医院管理局结核病控制协调委员会下属的潜在结核病感染工作组审查和评估了当地和国际科学证据,并制定了关于使用抗肿瘤坏死因子生物制剂的患者LTBI管理的指导声明。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Recommendations on Management of Latent Tuberculosis Infection in Patients Initiating Anti-tumor Necrosis Factor Biologics
Patients with immune-mediated inflammatory diseases on anti-tumor necrosis factor (TNF) agents are at increased risk of developing active tuberculosis (TB). Screening and treatment of latent tuberculosis infection (LTBI) with the use of a standard screening protocol is important in reducing the risk of TB reactivation during therapies with anti-TNF agents. The Latent Tuberculosis Infection Working Group under the Tuberculosis Control Coordinating Committee of the Department of Health and the Hospital Authority has reviewed and assessed local and international scientific evidence and formulated guideline statements on the management of LTBI in patients initiating anti-TNF biologics.
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