MAN NITOL治疗皮肤利什纳病的新方法

M. A.Kadir, Nidham A. Jaleel, Karim A. K. Al-Zaidaw
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引用次数: 0

摘要

本研究在HaWija区及周边村庄进行。选择了三个村庄(Al-Kadhemia、Sader A1 Naher、A1 Ameniea)。皮肤利什曼病的高发期在冬季(1996年12月至1997年3月)。阳性病例总数为227例(男111例,女116例)。发病率最高的是1-10岁的儿童。病灶内甘露醇溶液的有效性(93.89%)高于高渗氯化钠7%(87.50%),但与戊斯塔姆(96.20%)几乎相同。在所有三个治疗组中,大多数病变在第一次和第二次注射中治愈,但很少需要第三次注射。在所有三个治疗组中,疤痕均未出现或愈合程度最低。对照组病变在6-8周内均未治愈。结论20%rnannitol是治疗急性皮肤利什曼病的有效局部方法。20%甘露醇的疗效与戊斯塔姆相同,大于7%的“HSCS”。我
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NEW APPROACH FOR TREATMENT OF CUTANEOUS LEISHNIANIASIS BY MAN NITOL
The present study was carried outinHaWija District and surrounding villages. Three villages were chosen (Al-Kadhemia,Sader A1-Naher, A1-Ameniea). The high incidence rate of cutaneous leishmaniasis was during the Winter months (December 1996 to March 1997). The total positive cases were 227 ( 111 males and 116 females). The highest incidence rate was among childeren fiom 1-10 years old. Intralesional mannitol solution was shown to be more effective ( 93.89% ) than Hypertonic Sodium Chloride 7% (HSCS) ( 87.50% ) but almost identical to pentostam ( 96.20% ). Most of lesions were cured in first and second injection, in all three treated groups but few of them needed the third injection. In all three treated groups, the scar was absent or minimum afier healing. None of the control lesions cured-within 6-8 Weeks. It is concluded that 20% rnannitol is aneffective local method of treatment for acute cutaneous leishmaniasis. The efficacy of 20% of mannitol is identical to pentostam and greater than 7% “ HSCS”. i
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