霍奇金淋巴瘤与肺癌同时发生

R. Erdem, F. Aykaş, M. Göçer, O. In, Aslan, Mustafa Celik, G. Cetin, E. Kurtoğlu
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引用次数: 1

摘要

霍奇金淋巴瘤是一种罕见的肿瘤,其特点是发病年龄小,霍奇金和里德-斯特恩伯格(HRS)细胞来源于b淋巴细胞,即使患者出现晚期转移扩散,治愈率也很高。肺癌是世界上最常见的癌症,也是导致最多癌症死亡的原因。我们报告一例罕见的霍奇金淋巴瘤和肺癌并存的病例,患者为67岁男性。他最初表现为胸痛。Pet/ct示右肺肿块及颈部淋巴结。上颌前淋巴结活检符合经典霍奇金淋巴瘤。对于第二原发恶性肿瘤,我们也对右肺肿块进行了活检。病理显示为肺腺癌,随后行右上叶切除术。该患者接受吉西他滨加多西紫杉醇治疗肺癌。治疗结束时pet/ct显示完全缓解,包括颈部淋巴结。因此,我们没有对霍奇金淋巴瘤进行任何治疗。病人仍在接受病情缓解的随访。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Synchronous Occurrence of Hodgkin’s Lymphoma and Lung Cancer
Hodgkin lymphoma is an uncommon neoplasm that characterized young age of onset, Hodgkin and Reed-Sternberg (HRS) cells derived from B-lymphocytes and a high cure rate, even when the patient presents with advanced metastatic spread. Lung cancer is the most common cancer worldwide and is still responsible for the most cancer deaths. We present an extremely rare case of coexisting Hodgkin lymphoma and lung cancer in a 67-year-old male patient. He initially presented with chest pain. Pet/ct revealed mass in the right lung and lymph nodes in the neck. Biopsy from the premaxillary lymph node was compatible with classical Hodgkin lymphoma. In terms of second primary malignancy, a biopsy was also performed from the mass in the right lung. Pathology showed a pulmonary adenocarcinoma and a right upper lobectomy was then performed. This patient was treated with gemcitabine plus docetaxel for lung cancer. At the end of treatment pet/ct was complete response including lymph nodes in the neck. Therefore, we did not give any treatment for Hodgkin lymphoma. The patient is still being followed up in remission.
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