L. Álvarez-Hernández , J.E. Cuevas-Castillejos , H. Cuevas-Castillejos , C.M. Aboitiz-Rivera , R. Blachman-Braun
{"title":"兄弟姐妹巨细胞病毒感染的不同临床表现","authors":"L. Álvarez-Hernández , J.E. Cuevas-Castillejos , H. Cuevas-Castillejos , C.M. Aboitiz-Rivera , R. Blachman-Braun","doi":"10.1016/j.hgmx.2016.06.002","DOIUrl":null,"url":null,"abstract":"<div><p>In immunocompetent patients, human cytomegalovirus (CMV) infections are generally asymptomatic. Infection by this virus takes on particular importance during pregnancy owing to a risk of congenital infection occurring as a result of fetal transmission. In this article, we report the case of two siblings with this infection. The younger sibling had cystic microphthalmia, which was believed to be secondary to prenatal CMV infection. Given her status as an infectious carrier, she infected her older brother, who had signs and symptoms similar to those of infectious mononucleosis. CMV infection has a wide clinical spectrum, and prenatal CMV infection must be considered in patients within the differential diagnosis of eye malformations.</p></div>","PeriodicalId":31559,"journal":{"name":"Revista Medica del Hospital General de Mexico","volume":"80 3","pages":"Pages 174-177"},"PeriodicalIF":0.0000,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://sci-hub-pdf.com/10.1016/j.hgmx.2016.06.002","citationCount":"0","resultStr":"{\"title\":\"Different clinical manifestations in two siblings with cytomegalovirus infection\",\"authors\":\"L. Álvarez-Hernández , J.E. Cuevas-Castillejos , H. Cuevas-Castillejos , C.M. Aboitiz-Rivera , R. Blachman-Braun\",\"doi\":\"10.1016/j.hgmx.2016.06.002\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<div><p>In immunocompetent patients, human cytomegalovirus (CMV) infections are generally asymptomatic. Infection by this virus takes on particular importance during pregnancy owing to a risk of congenital infection occurring as a result of fetal transmission. In this article, we report the case of two siblings with this infection. The younger sibling had cystic microphthalmia, which was believed to be secondary to prenatal CMV infection. Given her status as an infectious carrier, she infected her older brother, who had signs and symptoms similar to those of infectious mononucleosis. CMV infection has a wide clinical spectrum, and prenatal CMV infection must be considered in patients within the differential diagnosis of eye malformations.</p></div>\",\"PeriodicalId\":31559,\"journal\":{\"name\":\"Revista Medica del Hospital General de Mexico\",\"volume\":\"80 3\",\"pages\":\"Pages 174-177\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://sci-hub-pdf.com/10.1016/j.hgmx.2016.06.002\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Revista Medica del Hospital General de Mexico\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://www.sciencedirect.com/science/article/pii/S0185106316300634\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Revista Medica del Hospital General de Mexico","FirstCategoryId":"1085","ListUrlMain":"https://www.sciencedirect.com/science/article/pii/S0185106316300634","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
Different clinical manifestations in two siblings with cytomegalovirus infection
In immunocompetent patients, human cytomegalovirus (CMV) infections are generally asymptomatic. Infection by this virus takes on particular importance during pregnancy owing to a risk of congenital infection occurring as a result of fetal transmission. In this article, we report the case of two siblings with this infection. The younger sibling had cystic microphthalmia, which was believed to be secondary to prenatal CMV infection. Given her status as an infectious carrier, she infected her older brother, who had signs and symptoms similar to those of infectious mononucleosis. CMV infection has a wide clinical spectrum, and prenatal CMV infection must be considered in patients within the differential diagnosis of eye malformations.
期刊介绍:
The Medical Journal of the Hospital General de Mexico is the official organ of the Medical Society of the Hospital General de Mexico. The journal accepts articles in Spanish or in English on the field of hospital medicine. The journal publishes original articles, clinical cases, reviews articles, history notes, issues on medical education, short communications and editorials at the invitation of the Society. All articles are double blind peer reviewed by at least 2 reviewers and finally classified as accepted or rejected by the Editorial Board.