诊断性DNA甲基组分析和WHO第5版中枢神经系统肿瘤分类。

IF 0.8 4区医学 Q4 CLINICAL NEUROLOGY

Clinical Neuropathology Pub Date : 2022-06-07 DOI:10.5414/NP301493

Stephan Frank, J. Hench

引用次数: 0

摘要

期待已久的第5版世界卫生组织脑肿瘤分类已经相当重视诊断DNA甲基化分析的重要性。在这篇文章中，作者比较讨论了基于阵列与纳米孔测序的甲基组分析方法的选择的实用方面以及一般优势和局限性。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Diagnostic DNA methylome profiling and the WHO 5th edition CNS tumor classification.

The long-awaited 5th edition of the WHO brain tumor classification has put considerable emphasis on the importance of diagnostic DNA methylation profiling. In this article, the authors comparatively discuss selected practical aspects as well as general advantages and limitations of array- versus nanopore sequencing-based approaches to methylome profiling.

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来源期刊

Clinical Neuropathology 医学-病理学

CiteScore

1.60

自引率

0.00%

发文量

审稿时长

>12 weeks

期刊介绍： Clinical Neuropathology appears bi-monthly and publishes reviews and editorials, original papers, short communications and reports on recent advances in the entire field of clinical neuropathology. Papers on experimental neuropathologic subjects are accepted if they bear a close relationship to human diseases. Correspondence (letters to the editors) and current information including book announcements will also be published.