生命科学研究团队协作与团队意识的社会支持

Q2 Decision Sciences
Source Code for Biology and Medicine Pub Date : 2019-07-08 eCollection Date: 2019-01-01 DOI:10.1186/s13029-019-0074-4
Delfina Malandrino, Ilaria Manno, Alberto Negro, Andrea Petta, Luigi Serra, Concita Cantarella, Vittorio Scarano
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引用次数: 0

摘要

背景:下一代测序(NGS)技术彻底改变了 "组学 "研究领域的格局。这些技术产生了大量信息,需要在样本制备、分析和特征描述方面具备特定的知识。此外,在使用生物信息学工具和方法对数据进行高效分析、解读和可视化时,还需要专业知识和能力。这些技能很少能在一个实验室内完成。更常见的情况是,样本在第一个实验室分离和纯化,测序由私人公司或专业实验室进行,而产生的数据则由第三组研究人员进行分析。在这种情况下,研究人员之间的支持、交流和信息共享是建立共同知识和实现项目目标的关键点:我们介绍了 ElGalaxy,这是一个为支持研究人员之间的协作和信息共享而设计开发的系统。具体来说,我们在生命科学研究人员通常采用的应用程序中集成了协作功能。因此,ElGalaxy 是工作流程管理系统 Galaxy 与社交网络引擎 Elgg 整合的结果:ElGalaxy 使从事同一实验的科学家能够合作和共享信息,讨论实验方法,评估实验过程中各个步骤以及整个活动的结果。ElGalaxy 还能提高团队意识,尤其是在与分属不同研究中心的研究人员一起进行实验时。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Social support for collaboration and group awareness in life science research teams.

Background: Next-generation sequencing (NGS) technologies have revolutionarily reshaped the landscape of '-omics' research areas. They produce a plethora of information requiring specific knowledge in sample preparation, analysis and characterization. Additionally, expertise and competencies are required when using bioinformatics tools and methods for efficient analysis, interpretation, and visualization of data. These skills are rarely covered in a single laboratory. More often the samples are isolated and purified in a first laboratory, sequencing is performed by a private company or a specialized lab, while the produced data are analyzed by a third group of researchers. In this scenario, the support, the communication, and the information sharing among researchers represent the key points to build a common knowledge and to meet the project objectives.

Results: We present ElGalaxy, a system designed and developed to support collaboration and information sharing among researchers. Specifically, we integrated collaborative functionalities within an application usually adopted by Life Science researchers. ElGalaxy, therefore, is the result of the integration of Galaxy, i.e., a Workflow Management System, with Elgg, i.e., a Social Network Engine.

Conclusions: ElGalaxy enables scientists, that work on the same experiment, to collaborate and share information, to discuss about methods, and to evaluate results of the individual steps, as well as of entire activities, performed during their experiments. ElGalaxy also allows a greater team awareness, especially when experiments are carried out with researchers which belong to different and distributed research centers.

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来源期刊
Source Code for Biology and Medicine
Source Code for Biology and Medicine Decision Sciences-Information Systems and Management
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期刊介绍: Source Code for Biology and Medicine is a peer-reviewed open access, online journal that publishes articles on source code employed over a wide range of applications in biology and medicine. The journal"s aim is to publish source code for distribution and use in the public domain in order to advance biological and medical research. Through this dissemination, it may be possible to shorten the time required for solving certain computational problems for which there is limited source code availability or resources.
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