成功的管理皮肤脓肿引起的白色念珠菌在一个非常低出生体重的新生儿

IF 0.2 Q4 PEDIATRICS
V. Vaddi, Medha Goyal, Dwayne Mascarenhas, A. Haribalakrishna
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引用次数: 2

摘要

真菌性败血症是新生儿重症监护病房中一种危险的感染,与显著的死亡率和神经发育后遗症相关。非常低的出生体重和非常早产的新生儿通常易患此病,表现从皮肤粘膜到侵入性器官受累不等。及时识别和治疗适当的抗真菌药物可改善生存和神经发育结果。在这个报告中,我们描述了一个罕见的皮肤病表现形式的皮肤真菌脓肿与尿路累及新生儿。诊断是基于脓液涂片检查和培养提示白色念珠菌的芽殖酵母细胞。危险因素包括出生体重<1500 g、放置中央血管导管、气管插管、肠外营养、手术干预和使用广谱抗生素。行两性霉素B去氧胆碱及脓肿切开引流,成功控制脓肿。本报告强调考虑念珠菌作为皮肤脓肿的病原,在早产的情况下与真菌感染的危险因素。系统传播的评估是强制性的,适当的抗真菌药物管理对生存至关重要。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
Successful management of a cutaneous abscess caused by Candida albicans in a very low birth weight neonate
Fungal sepsis is a sinister infection in the neonatal intensive care unit associated with significant mortality and neurodevelopment sequelae. Very low birth weight and very preterm neonates are often predisposed and manifestations range from mucocutaneous to invasive organ involvement. Prompt recognition and treatment with appropriate antifungal improve survival and neurodevelopmental outcomes. In this report, we describe a neonate with rare dermatological manifestation in the form of a cutaneous fungal abscess with urinary tract involvement. The diagnosis was based on budding yeast cells seen on pus smear examination and culture suggestive of Candida albicans. Risk factors included birth weight <1500 g, placement of central vascular catheter, endotracheal tube, parenteral nutrition, surgical intervention, and use of broad-spectrum antibiotics. Amphotericin B deoxycholate and incision and drainage of the abscess were done to manage the abscess successfully. This report highlights the consideration of Candida as an etiological agent for cutaneous abscesses, in case of preterms with risk factors for fungal infection. Evaluation for systemic dissemination is mandatory and management with appropriate antifungal agents is critical for survival.
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来源期刊
自引率
0.00%
发文量
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期刊介绍: The JCN publishes original articles, clinical reviews and research reports which encompass both basic science and clinical research including randomized trials, observational studies and epidemiology.
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