带有dna链接的复制子的倒绕模型

Q2 Agricultural and Biological Sciences

Biomath Pub Date : 2020-02-23 DOI:10.11145/j.biomath.2020.01.047

A. A. Mohamad, T. Yashiro

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引用次数: 2

摘要

双链DNA具有双螺旋结构，它是由固定在两端的细长扭曲带来模拟的。DNA链是真核细胞核中这种DNA片段的拓扑模型。在细胞周期中，DNA被复制并分布到新的细胞中。复杂的复制过程遵循半保守模式，即每个主链都保留在复制的DNA中。这可以用dna链的分裂过程来解释。为了分裂dna链，需要进行解结操作。提出了一种递归解结方法，有效地减少了缠绕次数。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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A rewinding model for replicons with DNA-links

A double strand DNA has a double helical structure and it is modeled by a thin long twisted ribbon fixed at the both ends. A DNA-link is a topological model of such a DNA segment in the nuclear of a eukaryotic cell. In the cell cycle, the DNA is replicated and distributed into new cells. The complicated replication process follows the semi-conservative scheme in which each backbone string is preserved in the replicated DNA. This is interpreted in terms of splitting process of the DNA-link. In order to split the DNA-link, unknotting operations are required. This paper presents a recursive unknotting operations, which efficiently reduce the number of twistings.

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来源期刊

Biomath Agricultural and Biological Sciences-Agricultural and Biological Sciences (miscellaneous)

CiteScore

2.20

自引率

0.00%

发文量

审稿时长

20 weeks