败血症相关性脑病的治疗进展

Q4 Medicine

中华实用儿科临床杂志 Pub Date : 2020-04-08 DOI:10.3760/CMA.J.CN101070-20200309-00356

Yibing Cheng, Meng Wang

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引用次数: 0

摘要

败血症相关性脑病（SAE）是败血症的常见并发症。未来可能发展的认知障碍不仅会降低生活质量，而且这种并发症患者的死亡率也很高。迄今为止，尚无明确的发病机制特征，也没有开发出特定的治疗方法。败血症的综合治疗是最常用的治疗方法。然而，脑病的治疗方法仍在研究中。未来应开发能够减少SAE引起的炎症、保护血脑屏障、抑制神经递质异常和抑制其他关键病理生理损伤的治疗方法，以防止SAE对患者造成永久性脑功能损伤。关键词：败血症；脑病；治疗

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Progress in sepsis-associated encephalopathy therapy

Sepsis-associated encephalopathy (SAE) is a common complication of sepsis.Not only the cognitive impairment which may develop in the future can reduce the quality of life, but also there is a high mortality in patients with this complication.There is no clear pathogenesis characterized and no specific therapy developed up to date.The synthetic treatment for sepsis is the most commonly used therapy.However, the treatment for encephalopathy is still under research.Therapy that can reduce inflammation caused by SAE, protect the blood-brain barrier, inhibit neurotransmitter abnormality, and restrain other key pathophysiology injuries should be developed in the future to prevent the permanent brain functional damage caused by SAE in patients. Key words: Sepsis; Encephalopathy; Treatment

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来源期刊

中华实用儿科临床杂志 Medicine-Pediatrics, Perinatology and Child Health

CiteScore

0.60

自引率

0.00%

发文量

14243

期刊介绍： Chinese Journal of Applied Clinical Pediatrics ( semi-monthly ) is a core journal of paediatrics under the supervision of China Association for Science and Technology, sponsored by Chinese Medical Association and undertaken by Xinxiang Medical College. Founded in 1986, it is openly circulated both at home and abroad. The journal has several columns, such as Expert Forum, Experimental Research and Paediatric Surgery, which are mainly for paediatric medical workers and medical researchers in hospitals. Its purpose is to reflect the new theories and technologies in paediatric medicine and scientific research at home and abroad, and to promote academic exchanges. Chinese Journal of Applied Clinical Pediatrics is a source journal of China Science Citation Database (CSCD), a core journal of Peking University, a source journal of Chinese science and technology paper statistics (China Science and Technology Core Journals), a core academic journal of RCCSE, a high-quality scientific and technical journal of China, a high-quality scientific and technical journal of China Association for Science and Technology, and a high-quality scientific and technical journal of China Biomedical Science and Technology Association. We have been published in China Biomedical Literature Database (SinoMed), China Knowledge Network, Wanfang Data Knowledge Service Platform, China Academic Journal Abstracts, Scopus Database, Chemical Abstracts (USA), Japan Science and Technology Agency (JSTA) Database, Copernicus Abstracts (Poland), Abstracts of the Centre for Agricultural and Biological Sciences (CABS) of the United Kingdom, Cambridge Scientific Abstracts ProQuest Database, WHO Medical Journal of the Western Pacific Region (WMPR), and WHO Medical Journal of the Western Pacific Region (WMPR) of the United States. We have been included in dozens of authoritative databases at home and abroad, such as WHO Western Pacific Region Index of Medicine (WPRIM), Ullrich's Guide to Periodicals, and so on.